LRIG3 and LMO7

Number of citations of the paper that reports this interaction (PubMedID 30429017)
6

Data Source:
BioGRID (two hybrid)

		LRIG3	LMO7
Description		leucine rich repeats and immunoglobulin like domains 3	LIM domain 7
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Integral Component Of Membrane Cytoplasmic Vesicle Membrane Extracellular Matrix	Ubiquitin Ligase Complex Nucleus Nuclear Envelope Cytoplasm Cytosol Focal Adhesion Cell Surface Apical Plasma Membrane
	Molecular Function	Protein Binding	Ubiquitin-protein Transferase Activity Metal Ion Binding
	Biological Process	Otolith Morphogenesis	Protein Ubiquitination Regulation Of Signaling Regulation Of Cell Adhesion Positive Regulation Of Transcription By RNA Polymerase II
Pathways			Neddylation Signaling by ALK fusions and activated point mutants Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Heart failure ( 20445134) Hematocrit ( 29403010) Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid) ( 24823311)	Cutaneous melanoma or hair colour ( 32341527) Glaucoma (multi-trait analysis) ( 31959993) Glaucoma (primary open-angle) ( 33627673 29449654) Initial pursuit acceleration ( 29064472) Initial pursuit acceleration in psychotic disorders ( 29064472) Intraocular pressure ( 29617998 29785010 31959993 30054594) Mean corpuscular hemoglobin ( 32888494) Multiple system atrophy (pathologically confirmed) ( 27629089) Obsessive-compulsive disorder ( 30456828) Type 1 diabetes ( 21980299)
Interacting Genes		3 interacting genes: LIMCH1 LMO7 MTDH	12 interacting genes: ABCA1 CALM1 EMD LRIG3 MDM2 PKM RHOU SRPK2 SUMO2 UBAC2 YWHAG YWHAQ
Entrez ID		121227	4008
HPRD ID		08317	05078
Ensembl ID		ENSG00000139263	ENSG00000136153
Uniprot IDs		C9K080 Q6UXM1	A0A0A0MTE2 E9PMT2 F8J2B5 F8WD26 Q8WWI1
PDB IDs			2EAQ
Enriched GO Terms of Interacting Partners?
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