FCER2 and ATF7

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		FCER2	ATF7
Description		Fc fragment of IgE receptor II	activating transcription factor 7
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Extracellular Exosome	Chromosome, Telomeric Region Chromatin Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Integrin Binding Protein Binding IgE Binding Carbohydrate Binding Metal Ion Binding	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Coactivator Binding DNA-binding Transcription Factor Activity Protein Binding Enzyme Binding CAMP Response Element Binding Metal Ion Binding Mitogen-activated Protein Kinase Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Positive Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin Positive Regulation Of Nitric-oxide Synthase Activity Positive Regulation Of Killing Of Cells Of Other Organism Positive Regulation Of Nitric-oxide Synthase Biosynthetic Process	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways		NOTCH2 intracellular domain regulates transcription Interleukin-10 signaling Interleukin-4 and Interleukin-13 signaling
Drugs		Lumiliximab	Pseudoephedrine
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269) Post bronchodilator FEV1 ( 26634245)	Basophil count ( 32888494) Electroencephalogram traits ( 25387704) Heel bone mineral density ( 30598549) Height ( 21998595 25429064 31562340 20189936) Lymphocyte percentage of white cells ( 32888494) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		5 interacting genes: ATF7 CR2 FYN ITGAX ITGB2	17 interacting genes: ATF2 FAM9B FCER2 FOS KASH5 MAPK9 MBD3 MITD1 OCIAD1 PTP4A1 PTP4A2 TAF12 TAF4 TAOK3 TMEM239 URI1 YY1
Entrez ID		2208	11016
HPRD ID		01049	06968
Ensembl ID		ENSG00000104921	ENSG00000170653
Uniprot IDs		K3W4U1 P06734	P17544
PDB IDs		1HLI 1KJE 1T8C 1T8D 2H2R 2H2T 4EZM 4G96 4G9A 4GI0 4GJ0 4GJX 4GK1 4GKO 4J6J 4J6K 4J6L 4J6M 4J6N 4J6P 4J6Q 4KI1 5LGK
Enriched GO Terms of Interacting Partners?
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