PTK2B and SKAP2

  • Number of citations of the paper that reports this interaction (PubMedID 12893833)
  • 15
  • Data Source:
  • BioGRID (affinity chromatography technology, two hybrid, affinity chromatography technology)

PTK2B

SKAP2

Description protein tyrosine kinase 2 beta src kinase associated phosphoprotein 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Chronic venous disease ( 28374850)
  • Disease free survival in colon cancer ( 31811950)
  • Erosive tooth wear (severe vs non-severe) ( 29898447)
  • Erosive tooth wear (severe vs none or mild) ( 29898447)
  • FEV1 ( 30804560)
  • Hip index ( 34021172)
  • Lung function (FVC) ( 30804560)
  • Lymphocyte counts ( 32888494)
  • Lymphocyte percentage of white cells ( 32888494)
  • Macular thickness ( 30535121)
  • Peak expiratory flow ( 30804560)
  • Small cell lung carcinoma ( 28604730)
  • Survival in colon cancer ( 31811950)
  • Systemic lupus erythematosus ( 28714469)
Interacting Genes 69 interacting genes: ARHGAP21 ARHGAP5 ASAP1 ASAP2 BCAR1 CBL CCR5 CRK DLG3 DLG4 DLGAP3 EFS EGFR ERBB2 ERBB3 EWSR1 FGFR2 FGFR3 FLT1 FYN GNA13 GRB2 GRIN2A GSN IL7R ITGB2 ITGB3 JAK1 JAK2 JAK3 KCNA2 LCK LPXN LYN MAP3K4 MAPT MATK MCAM MYH2 NEDD9 NPHP1 PDCD6IP PDPK1 PIK3R1 PITPNM1 PITPNM2 PITPNM3 PRKCD PTK2 PTPN11 PTPN12 PTPN6 PXN RASA1 RB1CC1 SH2D3C SHC1 SKAP2 SLC2A1 SNCA SORBS2 SRC STAP1 STAT3 SYK TGFB1I1 TLN1 VAV1 ZAP70 20 interacting genes: APP BLK DNAJB6 FAM102A FASLG FGR FRK FYB1 FYN HCK KHDRBS1 LCK LYN NCK2 PRAM1 PTK2B SRC SRMS TGFBR1 YES1
Entrez ID 2185 8935
HPRD ID 03131 05558
Ensembl ID ENSG00000120899 ENSG00000005020
Uniprot IDs Q14289 B7Z5R3 O75563
PDB IDs 2FO6 2LK4 3CC6 3ET7 3FZO 3FZP 3FZR 3FZS 3FZT 3GM1 3GM2 3GM3 3H3C 3U3F 4EKU 4H1J 4H1M 4R32 4XEF 4XEK 4XEV 5TO8 5TOB 6LF3 3OMH
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?