HACD2 and SMIM1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		HACD2	SMIM1
Description		3-hydroxyacyl-CoA dehydratase 2	small integral membrane protein 1 (Vel blood group)
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Endoplasmic Reticulum Membrane	Plasma Membrane Cell Surface Integral Component Of Membrane
	Molecular Function	Protein Tyrosine Phosphatase Activity Protein Binding 3-hydroxyacyl-CoA Dehydratase Activity Enzyme Binding 3R-hydroxyacyl-CoA Dehydratase Activity Very-long-chain 3-hydroxyacyl-CoA Dehydratase Activity 3-hydroxy-arachidoyl-CoA Dehydratase Activity 3-hydroxy-behenoyl-CoA Dehydratase Activity 3-hydroxy-lignoceroyl-CoA Dehydratase Activity	Protein Binding Protein Homodimerization Activity
	Biological Process	Sphingolipid Biosynthetic Process Fatty Acid Elongation Long-chain Fatty-acyl-CoA Biosynthetic Process Very Long-chain Fatty Acid Biosynthetic Process
Pathways		Synthesis of very long-chain fatty acyl-CoAs
Drugs
Diseases
GWAS		Gestational age at birth (maternal effect) ( 28877031)	Glycated hemoglobin levels ( 34059833) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494 27863252) Mean corpuscular hemoglobin concentration ( 32888494 27863252) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494 27863252) Red cell distribution width ( 32888494 27863252 28957414) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252)
Interacting Genes		6 interacting genes: BCAP31 CREB3L1 FAM209A SMIM1 TMX2 UBC	56 interacting genes: ANKS6 AQP6 ASZ1 BCL2L13 BIK CD74 CISD2 COMT CREB3L1 CYB561 EBP ERGIC3 FAM174A FAM209A FAM210B FCER1G FFAR2 FNDC9 GJA8 GJB5 HACD2 HSD17B13 ICAM3 JAGN1 KIR2DL3 LHFPL5 LRP10 LRRC4C MFF MFSD6 MUC1 NAALAD2 NDUFAF2 PVR REEP4 RELL2 RETREG3 SAR1A SCN3B SDC3 SIGLEC7 SLC10A6 SLC18A1 SLC26A11 STING1 STX1A TM4SF19 TMEM154 TMEM31 TMEM45B TMEM51 TMEM52B TMEM86B TMPRSS2 TMX2 ZDHHC15
Entrez ID		201562	388588
HPRD ID		17930
Ensembl ID		ENSG00000206527	ENSG00000235169
Uniprot IDs		Q6Y1H2	B2RUZ4 M4WDD3
PDB IDs
Enriched GO Terms of Interacting Partners?
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