ARL13B and HMOX2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ARL13B	HMOX2
Description		ADP ribosylation factor like GTPase 13B	heme oxygenase 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Cilium Axoneme Motile Cilium Ciliary Membrane Non-motile Cilium	Endoplasmic Reticulum Membrane Plasma Membrane Membrane Specific Granule Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding	Heme Oxygenase (decyclizing) Activity Protein Binding Heme Binding Metal Ion Binding
	Biological Process	Heart Looping Smoothened Signaling Pathway Dorsal/ventral Pattern Formation Response To Lithium Ion Neural Tube Patterning Interneuron Migration From The Subpallium To The Cortex Formation Of Radial Glial Scaffolds Cilium Assembly Left/right Axis Specification Receptor Localization To Non-motile Cilium Non-motile Cilium Assembly	Response To Hypoxia Heme Oxidation Response To Oxidative Stress Heme Catabolic Process Iron Ion Homeostasis
Pathways		ARL13B-mediated ciliary trafficking of INPP5E RHOQ GTPase cycle RHOJ GTPase cycle Chaperone Mediated Autophagy Late endosomal microautophagy Aggrephagy Aggrephagy	Heme degradation Neutrophil degranulation RHOA GTPase cycle Iron uptake and transport Cytoprotection by HMOX1
Drugs			NADH Stannsoporfin
Diseases
GWAS			Erectile dysfunction ( 30583798)
Interacting Genes		134 interacting genes: ACSF2 AIG1 ALG3 ANKRD46 AOC3 AQP10 ARL6 B4GALNT2 BMP10 BNIP3 BRICD5 C1GALT1 C2CD2L C4orf3 CCDC167 CCL4 CCL4L2 CD151 CD302 CD53 CDIPT CFHR5 CLDN4 CLDN8 CLEC4G CLEC7A CLN6 CMTM3 CMTM7 COL8A2 CRYBG3 CSGALNACT2 CTSA CXCL16 CYB561D2 DHFR2 EBP EMP1 ENTPD3 FAXDC2 FDFT1 FKBP8 FUNDC2 FXYD6 GAD2 GIMAP1 GIMAP5 GJB2 GOSR2 GPR37L1 HMOX1 HMOX2 HOMER3 ICMT ITGAM JAGN1 KCNJ2 KLRG1 LEPROTL1 LPAR3 MAL2 MALL MMD MOSPD3 MUCL1 MYADML2 NAT8 NINJ2 NKG7 NRM NUCB2 ORMDL1 ORMDL3 PAEP PDZK1IP1 PGAP2 PLN PLP1 PLPP4 PLPPR2 PMP22 PRB1 PTPN9 RIOX2 RTP2 S100A2 SACM1L SEMA4G SLC13A3 SLC2A5 SLC35A1 SLC35B1 SLC38A7 SLC39A2 SMAGP SPN STRIT1 STX1A STX7 TECR TEX264 TFRC THSD7A THSD7B TM6SF2 TMEM11 TMEM121 TMEM128 TMEM14C TMEM187 TMEM190 TMEM218 TMEM229B TMEM254 TMEM43 TMEM54 TMEM65 TMEM79 TMEM86B TMEM97 TMUB2 TNFRSF10C TNMD TRARG1 TSPO2 UBE2I VAMP1 VAMP2 VAMP3 VAMP4 VSTM1 WFDC2 YIPF6 ZDHHC15	66 interacting genes: A2M APP AQP6 ARL13B ASGR2 ATP5F1B BCL2L13 BLOC1S2 CCR2 CD79A CEBPZ CEP126 COPS6 CRB3 CSNK2A1 EBP EEF1G EIF3C ELOVL4 ERGIC3 F2RL1 FAM209A FAM210B GET1 GIT1 GPR152 GPRASP1 GPX8 HAP1 IMMT INPP5K ITFG1 JADE1 KCNJ6 KCNMA1 LAPTM5 LRIF1 MARK3 MED31 MGST3 MTNR1A NDUFS2 NKRF NR3C1 PLXNB2 PTGER4 RBBP4 RETREG3 RNASEK SAR1A SETDB1 SGPL1 SHC1 SKA2 SLC30A8 SMO SNX5 SNX7 SSMEM1 STOM SYT1 TMEM14B TMX2 VMA21 ZFP28 ZNF746
Entrez ID		200894	3163
HPRD ID		12334	00783
Ensembl ID		ENSG00000169379	ENSG00000103415
Uniprot IDs		Q3SXY8	A0A087WT44 B3KSE0 P30519
PDB IDs			2Q32 2QPP 2RGZ 4WMH 5UC8 5UC9 5UCA
Enriched GO Terms of Interacting Partners?
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