ELF5 and GLRX2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ELF5	GLRX2
Description		E74 like ETS transcription factor 5	glutaredoxin 2
Image
GO Annotations	Cellular Component	Chromatin Nucleus	Nucleus Nucleoplasm Mitochondrion Mitochondrial Matrix Dendrite Neuronal Cell Body Intracellular Membrane-bounded Organelle
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding	Protein Disulfide Isomerase Activity Protein Binding Arsenate Reductase (glutaredoxin) Activity Electron Transfer Activity Glutathione Disulfide Oxidoreductase Activity Metal Ion Binding 2 Iron, 2 Sulfur Cluster Binding Glutathione Oxidoreductase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Cell Differentiation	Regulation Of Transcription, DNA-templated Glutathione Metabolic Process Apoptotic Process Aging Response To Temperature Stimulus Regulation Of Signal Transduction Response To Organic Substance Electron Transport Chain Cell Differentiation DNA Protection Response To Hydrogen Peroxide Cell Redox Homeostasis Response To Redox State Cellular Response To Superoxide
Pathways
Drugs			Glutathione
Diseases
GWAS		β2-Glycoprotein I (β2-GPI) plasma levels ( 23279374) Blood protein levels ( 28240269) Metabolite levels ( 23823483)	Blood protein levels ( 29875488)
Interacting Genes		10 interacting genes: ACTR2 FRZB GLRX2 NFE2 NFE2L2 NRIP2 RPS15A SIRT6 SS18L1 UBQLN4	6 interacting genes: DCXR DENND1B ELF5 FBXO7 NUTF2 TXNRD1
Entrez ID		2001	51022
HPRD ID		05525	12112
Ensembl ID		ENSG00000135374	ENSG00000023572
Uniprot IDs		A0A087X1W9 A8K443 Q9UKW6	Q9NS18
PDB IDs		1WWX	2CQ9 2FLS 2HT9
Enriched GO Terms of Interacting Partners?
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