ELANE and TGFA

  • Number of citations of the paper that reports this interaction (PubMedID 15245434)
  • 16
  • Data Source:
  • HPRD (in vitro)

ELANE

TGFA

Description elastase, neutrophil expressed transforming growth factor alpha
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acne (severe) ( 24927181)
  • Cough in response to angiotensin-converting enzyme inhibitor drugs ( 28084903)
  • Hair shape ( 29220522)
  • Hand grip strength ( 29691431 29313844)
  • Heel bone mineral density ( 30598549)
  • Hip minimal joint space width ( 27701424)
  • Longevity ( 20834067)
  • Low hand grip strength (60 years and older) (EWGSOP) ( 33510174)
  • Low hand grip strength (60 years and older) (FNIH) ( 33510174)
  • Neutrophil count ( 21507922)
  • Obesity-related traits ( 23251661)
  • Osteoarthritis ( 30664745)
  • Pulse pressure in young-onset hypertension ( 24892410)
  • Response to citalopram or escitalopram in depression ( 27622933)
  • Response to esketamine in treatment resistant depression ( 32724131)
  • Severe progression in rheumatoid arthritis ( 29065906)
  • Superior frontal gyrus grey matter volume ( 25335168)
Interacting Genes 30 interacting genes: CAMP CSF3 CSF3R CXCL12 CXCR4 ELN F2R F2RL1 F5 GRN ITGAM KNG1 LPA LRP1 NOTCH2NLA SDC1 SERPINA1 SERPINA3 SERPINB1 SERPINB13 SERPIND1 SERPINE1 SERPINF2 SERPING1 SLPI TFPI TGFA THBS1 VCAM1 YARS1 17 interacting genes: ADAM10 ADAM17 EGFR ELANE ERBB2 ERBB4 GORASP1 GORASP2 LEPROTL1 MAGI2 MAGI3 NKD2 RHBDD1 RHBDF1 SDCBP SGTA SNTA1
Entrez ID 1991 7039
HPRD ID 00554 07522
Ensembl ID ENSG00000197561 ENSG00000163235
Uniprot IDs P08246 E7EPT6 F8VNR3 P01135
PDB IDs 1B0F 1H1B 1HNE 1PPF 1PPG 2RG3 2Z7F 3Q76 3Q77 4NZL 4WVP 5A09 5A0A 5A0B 5A0C 5A8X 5A8Y 5A8Z 5ABW 6E69 6F5M 6SMA 7CBK 1GK5 1MOX 1YUF 1YUG 2TGF 3E50 3TGF 4TGF 5KN5
Enriched GO Terms of Interacting Partners?
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