Description |
transforming growth factor alpha |
ADAM metallopeptidase domain 17 |
Image |
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GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
- Acne (severe) ( 24927181)
- Cough in response to angiotensin-converting enzyme inhibitor drugs ( 28084903)
- Hair shape ( 29220522)
- Hand grip strength ( 29691431 29313844)
- Heel bone mineral density ( 30598549)
- Hip minimal joint space width ( 27701424)
- Longevity ( 20834067)
- Low hand grip strength (60 years and older) (EWGSOP) ( 33510174)
- Low hand grip strength (60 years and older) (FNIH) ( 33510174)
- Neutrophil count ( 21507922)
- Obesity-related traits ( 23251661)
- Osteoarthritis ( 30664745)
- Pulse pressure in young-onset hypertension ( 24892410)
- Response to citalopram or escitalopram in depression ( 27622933)
- Response to esketamine in treatment resistant depression ( 32724131)
- Severe progression in rheumatoid arthritis ( 29065906)
- Superior frontal gyrus grey matter volume ( 25335168)
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Interacting Genes |
17 interacting genes:
ADAM10
ADAM17
EGFR
ELANE
ERBB2
ERBB4
GORASP1
GORASP2
LEPROTL1
MAGI2
MAGI3
NKD2
RHBDD1
RHBDF1
SDCBP
SGTA
SNTA1
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15 interacting genes:
DLG1
ERBB4
FHL2
MAD2L1
MAD2L2
NOTCH1
PTPN3
SH3D19
TGFA
TIMP3
TNF
TNFRSF1A
TNFRSF1B
TNFSF11
YIF1A
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Entrez ID |
7039 |
6868 |
HPRD ID |
07522 |
04703 |
Ensembl ID |
ENSG00000163235
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ENSG00000151694
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Uniprot IDs |
E7EPT6
F8VNR3
P01135
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B2RNB2
P78536
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PDB IDs |
1GK5
1MOX
1YUF
1YUG
2TGF
3E50
3TGF
4TGF
5KN5
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1BKC
1ZXC
2A8H
2DDF
2FV5
2FV9
2I47
2M2F
2OI0
3B92
3CKI
3E8R
3EDZ
3EWJ
3G42
3KMC
3KME
3L0T
3L0V
3LE9
3LEA
3LGP
3O64
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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