ANO6 and MUC19

		ANO6	MUC19
Description		anoctamin 6	mucin 19, oligomeric
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Cell Surface Membrane Chloride Channel Complex Specific Granule Membrane Extracellular Exosome Tertiary Granule Membrane	Extracellular Region Golgi Lumen Plasma Membrane
	Molecular Function	Calcium Activated Cation Channel Activity Intracellular Calcium Activated Chloride Channel Activity Voltage-gated Ion Channel Activity Voltage-gated Chloride Channel Activity Chloride Channel Activity Protein Binding Phospholipid Scramblase Activity Metal Ion Binding Protein Dimerization Activity
	Biological Process	Dendritic Cell Chemotaxis Activation Of Blood Coagulation Via Clotting Cascade Cation Transport Chloride Transport Induction By Virus Of Host Cell-cell Fusion Blood Coagulation Plasma Membrane Phospholipid Scrambling Positive Regulation Of Bone Mineralization Bleb Assembly Ion Transmembrane Transport Positive Regulation Of Ion Transmembrane Transport Purinergic Nucleotide Receptor Signaling Pathway Sodium Ion Transmembrane Transport Positive Regulation Of Apoptotic Process Negative Regulation Of Cell Volume Pore Complex Assembly Transmembrane Transport Positive Regulation Of Phagocytosis, Engulfment Calcium Activated Phosphatidylserine Scrambling Calcium Activated Phosphatidylcholine Scrambling Calcium Ion Transmembrane Transport Positive Regulation Of Monocyte Chemotaxis Phosphatidylserine Exposure On Blood Platelet Chloride Transmembrane Transport Positive Regulation Of Potassium Ion Export Across Plasma Membrane Positive Regulation Of Endothelial Cell Apoptotic Process
Pathways		Stimuli-sensing channels Neutrophil degranulation	Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) Defective GALNT12 causes colorectal cancer 1 (CRCS1) Dectin-2 family O-linked glycosylation of mucins Termination of O-glycan biosynthesis
Drugs
Diseases
GWAS		Ankylosing spondylitis ( 22138694) Insomnia ( 29520036) Urate levels in obese individuals ( 25811787) Waist circumference adjusted for body mass index ( 28552196)	Chromium levels ( 26025379) Crohn's disease ( 18587394 28067908 21102463) Daytime sleep phenotypes ( 27126917) Inflammatory bowel disease ( 28067908 23128233) Parent of origin effect on receptive language ability (paternal) ( 32635940)
Interacting Genes		9 interacting genes: ALG10B ARID2 C12orf40 CPNE8 GXYLT1 LRRK2 MUC19 PRICKLE1 SLC2A13	1 interacting genes: ANO6
Entrez ID		196527	283463
HPRD ID		18746	11377
Ensembl ID		ENSG00000177119	ENSG00000205592
Uniprot IDs		B3KX12 Q4KMQ2	Q7Z5P9
PDB IDs
Enriched GO Terms of Interacting Partners?
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