EHHADH and KRTAP10-7

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		EHHADH	KRTAP10-7
Description		enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase	keratin associated protein 10-7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Peroxisome Peroxisomal Matrix Cytosol	Cytosol Keratin Filament
	Molecular Function	3-hydroxyacyl-CoA Dehydrogenase Activity Dodecenoyl-CoA Delta-isomerase Activity Enoyl-CoA Hydratase Activity Protein Binding Long-chain-enoyl-CoA Hydratase Activity Long-chain-3-hydroxyacyl-CoA Dehydrogenase Activity Intramolecular Oxidoreductase Activity, Transposing C=C Bonds Enzyme Binding NAD+ Binding	Protein Binding Identical Protein Binding
	Biological Process	Fatty Acid Beta-oxidation Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase
Pathways		Beta-oxidation of very long chain fatty acids Peroxisomal protein import Peroxisomal protein import	Keratinization
Drugs		NADH
Diseases
GWAS		Cognitive performance ( 19734545) Major depressive disorder ( 27519822 21042317)
Interacting Genes		100 interacting genes: AARS2 ACTB ACTG1 ADARB1 ANKRD36B ARMC12 ARMCX3 BHLHE40 BOLL CAT CBS CCDC102B CCDC13 CDR2L CEP83 CISD2 CLDN18 CLDN5 CLK2 CMTM6 COQ9 CYB561 CYB561A3 DAAM2 DERL3 DES EMP1 ERGIC1 FGF14 FUNDC1 GAS8 GMCL1 GRIPAP1 HID1 HIP1 HSD17B11 HTATIP2 JAGN1 KCTD6 KCTD9 KRTAP10-7 KRTAP4-11 LCN2 LEPROTL1 LYPD5 LZTFL1 LZTS2 MAB21L3 MID1 MTUS2 NACC1 NECAB2 OPRM1 ORMDL1 PAQR8 PICK1 PNMA1 PNMA5 PPP1R12C PRKRA PSTPIP1 PTGES REL RNF4 RPRM RUSF1 SCARA5 SCP2 SDR16C5 SGCB SLC14A2 SLC39A2 SMIM5 SMN1 SMN2 SSNA1 SSX2IP SYNGR3 TMEM121 TMEM17 TMEM31 TMEM35A TNIP1 TPP2 TRAF1 TRIM21 TRIM23 TRIM27 TRIM41 TRIM5 TRIM54 TRIM55 TRIM63 VAC14 ZBTB10 ZBTB26 ZBTB8A ZBTB9 ZCCHC17 ZRANB1	282 interacting genes: AEN ALDH3B1 ANKRD36BP1 AP1M1 APP AQP1 AVPI1 B4GALT7 BAHD1 BCL6B BMP7 BRME1 BUD31 BYSL C8orf33 CARHSP1 CATIP CBX2 CCDC185 CCDC26 CCNG1 CDCA7L CHIC2 CHRD CHRNG CLK1 CLK4 CNNM3 COL8A1 CRCT1 CREB5 CRY2 CSNK1G1 CSNK1G2 CTNNBIP1 CTRC CXCL16 CYSRT1 DAAM2 DERL2 DHX57 DMRT3 DOCK2 E2F6 E4F1 EHHADH FADS6 FAM124B FAM161A FAM27E3 FAM74A4 FAM76B FARS2 GABARAPL1 GABARAPL2 GEM GLIDR GLP1R GNE GOLGA8EP GRN GSTP1 GUCD1 HBZ HCK HHEX HOXA1 HOXC8 HPCAL1 HSBP1 HSD3B7 IGSF8 ING5 INPP5D IQUB ITGB4 ITGB5 KLHL38 KRT20 KRT83 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP12-3 KRTAP26-1 KRTAP4-2 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1D LCE1F LCE2A LCE2B LCE2C LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LIMS2 LINC00242 LMNA LMO2 LRCH4 MAPKBP1 MCM5 MCRS1 MOBP MRGBP MXD3 MXI1 MYPOP NAA10 NAXD NECTIN2 NECTIN3 NKD1 NOL12 NOTCH2NLA NPBWR2 NPDC1 NTAQ1 NUBP2 NUDCD3 NUFIP2 OTX1 P2RY6 PCED1A PCSK5 PDE9A PDIA5 PDLIM5 PFKL PGAP6 PHLDA1 PIN1 POLL POM121L8P PPARD PRKAB2 PRM2 PRR13 PRR35 PTGDS PTGER3 PTPMT1 PVR R3HDM2 RNF175 RPF1 RPL11 RPL36AL RPS28 RPUSD3 RSPO2 RTN4RL1 RWDD2B SCNM1 SDCBP SHFL SLC23A1 SLC25A48 SLC6A20 SMCO4 SMCP SPACA9 SPATA24 SPATA3 SPATA8 SPG7 SPRY1 SSX2IP STAT3 STK16 SUV39H1 TAPBPL TCEA2 TCEANC TEDC2 TFAP2D THAP1 THAP6 TLE5 TMA16 TNP2 TNS2 TOR1A TREX1 TRIM42 TTPA TULP3 TXNDC5 TYRO3 UCP2 UXT VASN VGLL3 VTI1B WNT11 WT1 ZBTB24 ZBTB38 ZBTB48 ZBTB9 ZFP41 ZFYVE26 ZIM2 ZNF101 ZNF124 ZNF133 ZNF138 ZNF155 ZNF165 ZNF169 ZNF175 ZNF180 ZNF2 ZNF20 ZNF223 ZNF250 ZNF256 ZNF26 ZNF260 ZNF264 ZNF266 ZNF32 ZNF320 ZNF329 ZNF337 ZNF408 ZNF41 ZNF414 ZNF417 ZNF418 ZNF419 ZNF420 ZNF425 ZNF433 ZNF439 ZNF440 ZNF444 ZNF490 ZNF491 ZNF524 ZNF543 ZNF555 ZNF564 ZNF572 ZNF575 ZNF578 ZNF580 ZNF581 ZNF587 ZNF625 ZNF667 ZNF670 ZNF696 ZNF697 ZNF707 ZNF764 ZNF774 ZNF778 ZNF786 ZNF792 ZNF837 ZNF844 ZNF846 ZNHIT1 ZSCAN10 ZSCAN21 ZSCAN26
Entrez ID		1962	386675
HPRD ID		06125	11193
Ensembl ID		ENSG00000113790	ENSG00000272804
Uniprot IDs		Q08426	P60409
PDB IDs
Enriched GO Terms of Interacting Partners?
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