EHHADH and SSX2IP

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		EHHADH	SSX2IP
Description		enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase	SSX family member 2 interacting protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Peroxisome Peroxisomal Matrix Cytosol	Nucleus Cytoplasm Adherens Junction Cell Leading Edge Protein-containing Complex Centriolar Satellite Ciliary Basal Body
	Molecular Function	3-hydroxyacyl-CoA Dehydrogenase Activity Dodecenoyl-CoA Delta-isomerase Activity Enoyl-CoA Hydratase Activity Protein Binding Long-chain-enoyl-CoA Hydratase Activity Long-chain-3-hydroxyacyl-CoA Dehydrogenase Activity Intramolecular Oxidoreductase Activity, Transposing C=C Bonds Enzyme Binding NAD+ Binding	Protein Binding Protein Domain Specific Binding
	Biological Process	Fatty Acid Beta-oxidation Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase	Centrosome Cycle Cell Adhesion Regulation Of Rac Protein Signal Transduction Intraciliary Transport Involved In Cilium Assembly Cilium Assembly Regulation Of Cell Motility
Pathways		Beta-oxidation of very long chain fatty acids Peroxisomal protein import Peroxisomal protein import
Drugs		NADH
Diseases
GWAS		Cognitive performance ( 19734545) Major depressive disorder ( 27519822 21042317)	Urinary albumin-to-creatinine ratio in non-diabetics ( 26631737) Waist-to-hip ratio adjusted for body mass index ( 28430825)
Interacting Genes		100 interacting genes: AARS2 ACTB ACTG1 ADARB1 ANKRD36B ARMC12 ARMCX3 BHLHE40 BOLL CAT CBS CCDC102B CCDC13 CDR2L CEP83 CISD2 CLDN18 CLDN5 CLK2 CMTM6 COQ9 CYB561 CYB561A3 DAAM2 DERL3 DES EMP1 ERGIC1 FGF14 FUNDC1 GAS8 GMCL1 GRIPAP1 HID1 HIP1 HSD17B11 HTATIP2 JAGN1 KCTD6 KCTD9 KRTAP10-7 KRTAP4-11 LCN2 LEPROTL1 LYPD5 LZTFL1 LZTS2 MAB21L3 MID1 MTUS2 NACC1 NECAB2 OPRM1 ORMDL1 PAQR8 PICK1 PNMA1 PNMA5 PPP1R12C PRKRA PSTPIP1 PTGES REL RNF4 RPRM RUSF1 SCARA5 SCP2 SDR16C5 SGCB SLC14A2 SLC39A2 SMIM5 SMN1 SMN2 SSNA1 SSX2IP SYNGR3 TMEM121 TMEM17 TMEM31 TMEM35A TNIP1 TPP2 TRAF1 TRIM21 TRIM23 TRIM27 TRIM41 TRIM5 TRIM54 TRIM55 TRIM63 VAC14 ZBTB10 ZBTB26 ZBTB8A ZBTB9 ZCCHC17 ZRANB1	113 interacting genes: ABLIM3 ACTN1 ACTN2 AEN AFDN AP1M1 ARNT2 BCL6 BEX2 BRCA1 BYSL C11orf54 CARD9 CCDC187 CCDC198 CCHCR1 CCNH CDC23 CDC42 CDCA7L CHCHD3 DAXX DRG1 DVL2 EAF2 EHHADH EIF4A2 ERAL1 FAM124B FAM161A FAM214A FANCG FANCL FBF1 FNDC11 FRMD6 GEM GOLGA2 GOLGA8F GRAP2 HDAC4 HNRNPLL IKBKG INO80B KAT5 KDM1A KIF9 KIFC3 KLHL42 KRT15 KRT31 KRT40 KRTAP10-7 LATS1 LMO2 MCM7 MFAP1 MORN4 MOS MRPL53 NAA10 NDN NIF3L1 NOL12 NTAQ1 PHC2 PIMREG PKN1 PNMA1 POLL PRKAA1 PRKAB2 PRMT6 PRPF3 PRPF31 PSMA1 RNF6 SCNM1 SHFL SSX2 SSX3 SYT17 TBP TEAD4 TFIP11 TOP3B TRIM42 TRIM54 TSGA10IP TSTD2 TTC23 WDR5 XIAP YWHAQ YWHAZ ZBTB24 ZFYVE26 ZGPAT ZMAT2 ZNF124 ZNF202 ZNF250 ZNF3 ZNF408 ZNF417 ZNF438 ZNF587 ZNF648 ZNF688 ZNF71 ZNF792 ZRSR2 ZSCAN12
Entrez ID		1962	117178
HPRD ID		06125	10566
Ensembl ID		ENSG00000113790	ENSG00000117155
Uniprot IDs		Q08426	B7ZB07 Q9Y2D8
PDB IDs
Enriched GO Terms of Interacting Partners?
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