EIF2D and HEXB

Number of citations of the paper that reports this interaction (PubMedID 7299841)
3

Data Source:
HPRD (in vitro)

		EIF2D	HEXB
Description		eukaryotic translation initiation factor 2D	hexosaminidase subunit beta
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol Nuclear Body	Acrosomal Vesicle Extracellular Region Lysosome Membrane Azurophil Granule Lumen Azurophil Granule Lysosomal Lumen Cortical Granule Extracellular Exosome
	Molecular Function	Translation Initiation Factor Activity Signaling Receptor Activity	Beta-N-acetylhexosaminidase Activity Protein Binding Acetylglucosaminyltransferase Activity Identical Protein Binding N-acetyl-beta-D-galactosaminidase Activity
	Biological Process	Formation Of Translation Preinitiation Complex Intracellular Protein Transport Ribosome Disassembly IRES-dependent Viral Translational Initiation	Skeletal System Development Ganglioside Catabolic Process Cellular Calcium Ion Homeostasis Lysosome Organization Single Fertilization Penetration Of Zona Pellucida Sensory Perception Of Sound Locomotory Behavior Male Courtship Behavior Regulation Of Cell Shape Phospholipid Biosynthetic Process Oligosaccharide Catabolic Process Lipid Storage Glycosaminoglycan Metabolic Process Myelination Astrocyte Cell Migration Cellular Protein Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Oogenesis Neuromuscular Process Controlling Balance
Pathways			Glycosphingolipid metabolism Keratan sulfate degradation CS/DS degradation Hyaluronan uptake and degradation Defective HEXB causes GM2G2 Neutrophil degranulation
Drugs			Pyrimethamine 2-Acetamido-2-Deoxy-D-Glucono-1,5-Lactone N-Acetyl-glucosamine thiazoline (2R,3R,4S,5R)-2-acetamido-3,4-dihydroxy-5-hydroxymethyl-piperidine
Diseases
GWAS		Ceramide levels (C24:0) ( 32489964)	Gut microbiota relative abundance (unassigned genus belonging to family Clostridiales) ( 33208821) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917)
Interacting Genes		3 interacting genes: ACHE HEXB PTPRC	5 interacting genes: CSNK2B EIF2D FAM210B HOXA1 TMEM14B
Entrez ID		1939	3074
HPRD ID		01057	06043
Ensembl ID		ENSG00000143486	ENSG00000049860
Uniprot IDs		P41214	A0A024RAJ6 P07686 Q5URX0
PDB IDs		5OA3 5OA9 5W2F	1NOU 1NOW 1NP0 1O7A 1QBD 2GJX 2GK1 3LMY 5BRO
Enriched GO Terms of Interacting Partners?
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