HEXB

Description		hexosaminidase subunit beta
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GO Annotations	Cellular Component	Acrosomal Vesicle Extracellular Region Lysosome Membrane Azurophil Granule Lumen Azurophil Granule Lysosomal Lumen Cortical Granule Extracellular Exosome
	Molecular Function	Beta-N-acetylhexosaminidase Activity Protein Binding Acetylglucosaminyltransferase Activity Identical Protein Binding N-acetyl-beta-D-galactosaminidase Activity
	Biological Process	Skeletal System Development Ganglioside Catabolic Process Cellular Calcium Ion Homeostasis Lysosome Organization Single Fertilization Penetration Of Zona Pellucida Sensory Perception Of Sound Locomotory Behavior Male Courtship Behavior Regulation Of Cell Shape Phospholipid Biosynthetic Process Oligosaccharide Catabolic Process Lipid Storage Glycosaminoglycan Metabolic Process Myelination Astrocyte Cell Migration Cellular Protein Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Oogenesis Neuromuscular Process Controlling Balance
Pathways		Glycosphingolipid metabolism Keratan sulfate degradation CS/DS degradation Hyaluronan uptake and degradation Defective HEXB causes GM2G2 Neutrophil degranulation
Drugs		Pyrimethamine 2-Acetamido-2-Deoxy-D-Glucono-1,5-Lactone N-Acetyl-glucosamine thiazoline (2R,3R,4S,5R)-2-acetamido-3,4-dihydroxy-5-hydroxymethyl-piperidine
Diseases
GWAS		Gut microbiota relative abundance (unassigned genus belonging to family Clostridiales) ( 33208821) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917)
Interacting Genes		5 interacting genes: CSNK2B EIF2D FAM210B HOXA1 TMEM14B
Entrez ID		3074
HPRD ID		06043
Ensembl ID		ENSG00000049860
Uniprot IDs		A0A024RAJ6 P07686 Q5URX0
PDB IDs		1NOU 1NOW 1NP0 1O7A 1QBD 2GJX 2GK1 3LMY 5BRO
Enriched GO Terms of Interacting Partners?
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