EEF1A2 and TTLL12

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		EEF1A2	TTLL12
Description		eukaryotic translation elongation factor 1 alpha 2	tubulin tyrosine ligase like 12
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Eukaryotic Translation Elongation Factor 1 Complex Neuronal Cell Body Synapse Cytoplasmic Side Of Lysosomal Membrane	Nucleus Cytoplasm Microtubule Organizing Center Spindle Midbody
	Molecular Function	Translation Elongation Factor Activity GTPase Activity Protein Binding GTP Binding Translation Factor Activity, RNA Binding Protein Kinase Binding	Tubulin-tyrosine Ligase Activity Protein Binding ATP Binding Tubulin Binding Histone-lysine N-methyltransferase Activity H4K20me3 Modified Histone Binding
	Biological Process	Translation Translational Elongation Response To Inorganic Substance Positive Regulation Of Apoptotic Process Response To Electrical Stimulus Positive Regulation Of Lipid Kinase Activity Regulation Of Chaperone-mediated Autophagy	Cellular Protein Modification Process Regulation Of Mitotic Cell Cycle Innate Immune Response Negative Regulation Of Type I Interferon-mediated Signaling Pathway Regulation Of Histone H4-K20 Methylation
Pathways		Eukaryotic Translation Elongation	Carboxyterminal post-translational modifications of tubulin
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Prostate cancer ( 23535732) Serum metabolite levels ( 33031748)	Molar-incisor hypomineralization ( 23918034) Monocyte count ( 32888494 27863252) Platelet count ( 32888494) Plateletcrit ( 32888494)
Interacting Genes		11 interacting genes: ABTB1 CHRM4 ERG MAPK6 SMN1 STK11 SUMO2 TPT1 TSPY1 TTLL12 UBE3A	7 interacting genes: CSNK2A2 DNAJB1 EEF1A1 EEF1A2 FAM222B PRR35 SUMO2
Entrez ID		1917	23170
HPRD ID		04265	13782
Ensembl ID		ENSG00000101210	ENSG00000100304
Uniprot IDs		Q05639	A0A024R4U3 Q14166
PDB IDs		3C5J
Enriched GO Terms of Interacting Partners?
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