DSC2 and FHOD3

		DSC2	FHOD3
Description		desmocollin 2	formin homology 2 domain containing 3
Image			No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Plasma Membrane Cell-cell Junction Intercalated Disc Integral Component Of Membrane Desmosome Cytoplasmic Vesicle Extracellular Exosome	Cytoplasm Cytoskeleton Striated Muscle Thin Filament Z Disc
	Molecular Function	Calcium Ion Binding Protein Binding Cell Adhesive Protein Binding Involved In Bundle Of His Cell-Purkinje Myocyte Communication	Protein Binding Actin Filament Binding
	Biological Process	Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Cardiac Muscle Cell-cardiac Muscle Cell Adhesion Bundle Of His Cell-Purkinje Myocyte Adhesion Involved In Cell Communication Regulation Of Heart Rate By Cardiac Conduction Cell-cell Adhesion Regulation Of Ventricular Cardiac Muscle Cell Action Potential	Negative Regulation Of Actin Filament Polymerization Cortical Actin Cytoskeleton Organization Sarcomere Organization Actin Filament Network Formation Cardiac Myofibril Assembly
Pathways		Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Bronchopulmonary dysplasia ( 23897914) Metabolite levels ( 23823483) Response to immune checkpoint inhibitors in melanoma (immune-related adverse events) ( 33409738)	Adverse response to drug ( 30420678) Dilated cardiomyopathy ( 33495596) Dilated cardiomyopathy (MTAG) ( 33495596) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Heel bone mineral density ( 30598549) Height ( 31562340) Hypertrophic cardiomyopathy ( 33495596 33495597) Hypertrophic cardiomyopathy (MTAG) ( 33495596) Hypertrophic cardiomyopathy (sarcomere negative) ( 33495597) Obesity-related traits ( 23251661) Periodontal disease-related phenotype (Socransky) ( 24347629) Pulse pressure ( 27841878 30578418) QRS duration ( 27659466) Response to antipsychotic treatment ( 20195266) Resting heart rate ( 29769521 27798624) Spontaneous preterm birth with premature rupture of membranes ( 31194736)
Interacting Genes		12 interacting genes: CDC6 CELF4 CLK1 DSC3 DSG1 DSG2 FHOD3 ITSN1 JUP PKP2 PKP3 RO60	1 interacting genes: DSC2
Entrez ID		1824	80206
HPRD ID		00512	16894
Ensembl ID		ENSG00000134755	ENSG00000134775
Uniprot IDs		A0A3B3ISU0 Q02487	Q2V2M9
PDB IDs		5ERP 5J5J 7A7D
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?