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DSC2

Description desmocollin 2
Image
GO Annotations Cellular Component
  • Cornified Envelope
  • Plasma Membrane
  • Cell-cell Junction
  • Intercalated Disc
  • Integral Component Of Membrane
  • Desmosome
  • Cytoplasmic Vesicle
  • Extracellular Exosome
Molecular Function
  • Calcium Ion Binding
  • Protein Binding
  • Cell Adhesive Protein Binding Involved In Bundle Of His Cell-Purkinje Myocyte Communication
Biological Process
  • Cell Adhesion
  • Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules
  • Cardiac Muscle Cell-cardiac Muscle Cell Adhesion
  • Bundle Of His Cell-Purkinje Myocyte Adhesion Involved In Cell Communication
  • Regulation Of Heart Rate By Cardiac Conduction
  • Cell-cell Adhesion
  • Regulation Of Ventricular Cardiac Muscle Cell Action Potential
Pathways
  • Keratinization
  • Formation of the cornified envelope
Drugs
Diseases
GWAS
  • Blood protein levels ( 30072576 29875488)
  • Bronchopulmonary dysplasia ( 23897914)
  • Metabolite levels ( 23823483)
  • Response to immune checkpoint inhibitors in melanoma (immune-related adverse events) ( 33409738)
Interacting Genes 12 interacting genes: CDC6 CELF4 CLK1 DSC3 DSG1 DSG2 FHOD3 ITSN1 JUP PKP2 PKP3 RO60
Entrez ID 1824
HPRD ID 00512
Ensembl ID ENSG00000134755
Uniprot IDs A0A3B3ISU0 Q02487
PDB IDs 5ERP 5J5J 7A7D
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025