DPYSL2 and DPYSL5

Number of citations of the paper that reports this interaction (PubMedID 10956643)
51

Data Source:
HPRD (in vivo)

		DPYSL2	DPYSL5
Description		dihydropyrimidinase like 2	dihydropyrimidinase like 5
Image
GO Annotations	Cellular Component	Cytosol Microtubule Plasma Membrane Membrane Extracellular Exosome	Cytosol Dendrite Neuronal Cell Body
	Molecular Function	Dihydropyrimidinase Activity Protein Binding Microtubule Binding Identical Protein Binding	Dihydropyrimidinase Activity Protein Binding Microtubule Binding
	Biological Process	Nucleobase-containing Compound Metabolic Process Pyrimidine Nucleobase Catabolic Process Endocytosis Cytoskeleton Organization Signal Transduction Nervous System Development Axon Guidance Brain Development Regulation Of Axon Extension Regulation Of Neuron Differentiation	Pyrimidine Nucleobase Catabolic Process Signal Transduction Nervous System Development Axon Guidance
Pathways		CRMPs in Sema3A signaling Recycling pathway of L1	CRMPs in Sema3A signaling
Drugs		Artenimol
Diseases
GWAS		Barrett's esophagus or Esophageal adenocarcinoma ( 32918910) Barrett's esophagus or esophageal adenocarcinoma x sex interaction (1df test) ( 32918910) Barrett's esophagus or esophageal adenocarcinoma x sex interaction (2df test) ( 32918910) Bitter alcoholic beverage consumption ( 31046077) Brain morphology (MOSTest) ( 32665545) Diastolic blood pressure ( 30224653) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Fasting blood glucose ( 22581228) Fasting blood glucose (BMI interaction) ( 22581228) Fasting glucose ( 34059833) Fasting insulin ( 34059833) Obesity-related traits ( 23251661) Reflection (response to stress) ( 30886212) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Urate levels ( 31578528) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683) White blood cell count ( 32888494)
Interacting Genes		18 interacting genes: AP2A1 CDC42 CRMP1 DISC1 DPYSL3 DPYSL4 DPYSL5 GORASP2 GSK3B LEF1 NUMB PCM1 PLD2 ROCK1 TNIK TUBA4A TUBB UBE2I	10 interacting genes: APPL1 CFAP161 DARS2 DPYS DPYSL2 DPYSL3 DPYSL4 FBN2 FES HSPA5
Entrez ID		1808	56896
HPRD ID		03914	10522
Ensembl ID		ENSG00000092964	ENSG00000157851
Uniprot IDs		A0A1C7CYX9 Q16555 Q59GB4	Q9BPU6
PDB IDs		2GSE 2VM8 5LXX 5MKV 5MLE 5X1A 5X1C 5X1D 5YZ5 5YZA 5YZB 6JV9 6JVB	4B90 4B91 4B92
Enriched GO Terms of Interacting Partners?
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