DPYSL2 and DPYSL3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid, two hybrid, two hybrid)

		DPYSL2	DPYSL3
Description		dihydropyrimidinase like 2	dihydropyrimidinase like 3
Image
GO Annotations	Cellular Component	Cytosol Microtubule Plasma Membrane Membrane Extracellular Exosome	Extracellular Space Cytosol Lamellipodium Growth Cone Filamentous Actin Cell Body Synapse Exocytic Vesicle
	Molecular Function	Dihydropyrimidinase Activity Protein Binding Microtubule Binding Identical Protein Binding	Dihydropyrimidinase Activity Protein Binding SH3 Domain Binding Filamin Binding Chondroitin Sulfate Binding Identical Protein Binding
	Biological Process	Nucleobase-containing Compound Metabolic Process Pyrimidine Nucleobase Catabolic Process Endocytosis Cytoskeleton Organization Signal Transduction Nervous System Development Axon Guidance Brain Development Regulation Of Axon Extension Regulation Of Neuron Differentiation	Pyrimidine Nucleobase Catabolic Process Positive Regulation Of Neuron Projection Development Negative Regulation Of Neuron Projection Development Negative Regulation Of Cell Migration Neuron Development Response To Axon Injury Actin Filament Bundle Assembly Positive Regulation Of Filopodium Assembly Actin Crosslink Formation Cellular Response To Cytokine Stimulus
Pathways		CRMPs in Sema3A signaling Recycling pathway of L1	CRMPs in Sema3A signaling
Drugs		Artenimol
Diseases
GWAS		Barrett's esophagus or Esophageal adenocarcinoma ( 32918910) Barrett's esophagus or esophageal adenocarcinoma x sex interaction (1df test) ( 32918910) Barrett's esophagus or esophageal adenocarcinoma x sex interaction (2df test) ( 32918910) Bitter alcoholic beverage consumption ( 31046077) Brain morphology (MOSTest) ( 32665545) Diastolic blood pressure ( 30224653) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)	Brain morphology (MOSTest) ( 32665545) Excessive daytime sleepiness ( 27992416) Metabolite levels ( 23823483) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		18 interacting genes: AP2A1 CDC42 CRMP1 DISC1 DPYSL3 DPYSL4 DPYSL5 GORASP2 GSK3B LEF1 NUMB PCM1 PLD2 ROCK1 TNIK TUBA4A TUBB UBE2I	10 interacting genes: ACD CRMP1 DISC1 DPYSL2 DPYSL5 HYOU1 OTUD6A POT1 TERF1 TNIK
Entrez ID		1808	1809
HPRD ID		03914	03104
Ensembl ID		ENSG00000092964	ENSG00000113657
Uniprot IDs		A0A1C7CYX9 Q16555 Q59GB4	A0A140VK07 Q14195 Q6DEN2 Q8IXW6
PDB IDs		2GSE 2VM8 5LXX 5MKV 5MLE 5X1A 5X1C 5X1D 5YZ5 5YZA 5YZB 6JV9 6JVB	4BKN 4CNS 4CNT 4CNU
Enriched GO Terms of Interacting Partners?
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