DYNC1I2 and ATP5MC3

		DYNC1I2	ATP5MC3
Description		dynein cytoplasmic 1 intermediate chain 2	ATP synthase membrane subunit c locus 3
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Cytosol Cytoplasmic Dynein Complex Microtubule Vesicle	Mitochondrial Proton-transporting ATP Synthase Complex, Coupling Factor F(o) Mitochondrial Outer Membrane Integral Component Of Membrane Proton-transporting ATP Synthase Complex, Coupling Factor F(o)
	Molecular Function	Microtubule Motor Activity Protein Binding Dynein Light Chain Binding Dynein Heavy Chain Binding	Lipid Binding Proton Transmembrane Transporter Activity
	Biological Process	Microtubule-based Movement Transport Along Microtubule	ATP Synthesis Coupled Proton Transport
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Regulation of PLK1 Activity at G2/M Transition HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase AURKA Activation by TPX2 HCMV Early Events Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation	Formation of ATP by chemiosmotic coupling Cristae formation
Drugs
Diseases
GWAS		Hippocampal volume ( 25625606) Metabolite levels ( 23823483) Refractive error ( 32231278) Weight ( 28552196)
Interacting Genes		13 interacting genes: ACTN3 ATP5MC3 CCDC136 CDCA7 DCTN1 DYNLRB1 DYNLT1 DYNLT3 HOXD1 HOXD8 NECAB2 PNN PPFIA1	8 interacting genes: ABHD16A CTLA4 DYNC1I2 GLP1R MTNR1A TMEM31 TUBA4A VKORC1
Entrez ID		1781	518
HPRD ID		04512	04112
Ensembl ID		ENSG00000077380	ENSG00000154518
Uniprot IDs		A0A140VKE9 B4DPZ3 Q13409	P48201
PDB IDs		5JPW 6F1T 6F1U 6F1Z 6F38 6F3A
Enriched GO Terms of Interacting Partners?
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