DNM1 and PIN4

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		DNM1	PIN4
Description		dynamin 1	peptidylprolyl cis/trans isomerase, NIMA-interacting 4
Image
GO Annotations	Cellular Component	Photoreceptor Inner Segment Nucleoplasm Cytoplasm Golgi Apparatus Microtubule Plasma Membrane Synaptic Vesicle Membrane Membrane Coat Varicosity Synapse Extracellular Exosome Photoreceptor Ribbon Synapse Presynaptic Endocytic Zone Membrane Glutamatergic Synapse	Nucleoplasm Chromosome Nucleolus Mitochondrial Matrix Spindle
	Molecular Function	RNA Binding GTPase Activity Protein Binding GTP Binding Microtubule Binding Protein C-terminus Binding SH3 Domain Binding Protein Kinase Binding D2 Dopamine Receptor Binding Identical Protein Binding Protein-containing Complex Binding Nitric-oxide Synthase Binding	DNA Binding RNA Binding Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding
	Biological Process	G Protein-coupled Receptor Internalization Endocytosis Receptor-mediated Endocytosis Endosome Organization Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Receptor Internalization Synaptic Vesicle Endocytosis Modulation Of Chemical Synaptic Transmission Positive Regulation Of Synaptic Vesicle Endocytosis Toxin Transport Response To Amyloid-beta	Protein Peptidyl-prolyl Isomerization RRNA Processing
Pathways		Toll Like Receptor 4 (TLR4) Cascade Retrograde neurotrophin signalling Gap junction degradation Formation of annular gap junctions MHC class II antigen presentation EPH-ephrin mediated repulsion of cells Recycling pathway of L1 Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder ( 18839057) Body mass index ( 26426971) Coenzyme Q10 levels ( 27149984) Platelet distribution width ( 32888494)	Rosacea symptom severity ( 29771307)
Interacting Genes		47 interacting genes: AMPH AP2A2 ASB13 BIN1 CABIN1 CAV1 CDK5 CEP126 CLIC3 CLIC4 CLINT1 CTTN DNM2 DNMBP EPS15 FNBP1 GRB2 GRIN1 GRIN2D ITSN1 MAP3K10 MED31 MOB4 NCK1 NCK2 NME2 PACSIN1 PACSIN2 PACSIN3 PFN2 PIAS1 PIK3R1 PIN4 PLCG1 PRKCA PRNP RACK1 SH3GL1 SH3GL2 SH3GL3 SHANK2 SNAP25 SNX9 SRC SUMO1 TIMM50 UBE2I	19 interacting genes: ASCC2 CEP72 CSNK2A1 CSNK2A2 DNM1 EGFR ERBB2 ERBB3 ERBB4 EZH2 FAM9B FATE1 FBL FRMD1 MAD1L1 MAGEA11 PNMA1 SPTAN1 ZBTB9
Entrez ID		1759	5303
HPRD ID		03851	02219
Ensembl ID		ENSG00000106976	ENSG00000102309
Uniprot IDs		B4DK06 B7ZAC0 Q05193	Q9Y237
PDB IDs		1DYN 2DYN 2X2E 2X2F 3SNH 3ZYC 3ZYS 4UUD 4UUK 5D3Q 6DLU 6DLV 6S9A	1EQ3 1FJD 3UI4 3UI5 3UI6
Enriched GO Terms of Interacting Partners?
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