CLEC4C and KTN1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CLEC4C	KTN1
Description		C-type lectin domain family 4 member C	kinectin 1
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Secretory Granule Membrane Tertiary Granule Membrane Ficolin-1-rich Granule Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding Carbohydrate Binding Metal Ion Binding	RNA Binding Protein Binding Kinesin Binding Cadherin Binding
	Biological Process	Adaptive Immune Response Innate Immune Response	Microtubule-based Movement Protein Transport
Pathways		Dectin-2 family Neutrophil degranulation	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) RHO GTPases activate KTN1 Post-translational protein phosphorylation RHOA GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle RHOG GTPase cycle RND3 GTPase cycle RND2 GTPase cycle
Drugs
Diseases
GWAS		Blood protein levels ( 30072576)	Brain morphology (MOSTest) ( 32665545) Early spontaneous preterm birth ( 31194736) Lean body mass ( 28552196) Neurofibrillary tangles ( 31497858) Plasma anti-thyroglobulin levels ( 29678681) Subcortical brain region volumes ( 25607358)
Interacting Genes		3 interacting genes: CLDN22 KTN1 MAL	30 interacting genes: ABI1 BNIP3 CD3G CD68 CDC42 CLEC4C CLEC7A EEF1D FFAR2 IKBKE INPP5E KIF5B KIR2DL3 LHFPL5 M6PR MEOX2 MFSD14B PDCD1LG2 PLEKHA5 RAC1 RHOA RHOG SGTA SIRPA STOM SUSD3 SYNE4 SYNPR TMEM179B UBE2I
Entrez ID		170482	3895
HPRD ID		09453	02661
Ensembl ID		ENSG00000198178	ENSG00000126777
Uniprot IDs		Q8WTT0	A0A024R663 Q86UP2
PDB IDs		3WBP 3WBQ 3WBR 4ZES 4ZET
Enriched GO Terms of Interacting Partners?
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