CFD and HDHD2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
HPRD (two hybrid)

		CFD	HDHD2
Description		complement factor D	haloacid dehalogenase like hydrolase domain containing 2
Image
GO Annotations	Cellular Component	Extracellular Region Platelet Alpha Granule Lumen Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen	Extracellular Exosome
	Molecular Function	Serine-type Endopeptidase Activity Serine-type Peptidase Activity	Protein Binding Phosphatase Activity Enzyme Binding Metal Ion Binding
	Biological Process	Proteolysis Complement Activation Complement Activation, Alternative Pathway Notch Signaling Pathway Response To Bacterium	Biological_process Dephosphorylation
Pathways		Platelet degranulation Alternative complement activation Neutrophil degranulation
Drugs		2-Aminobenzyl alcohol 3,4-Dichloroisocoumarin
Diseases
GWAS		High light scatter reticulocyte percentage of red cells ( 32888494) Reticulocyte count ( 32888494)	Blood protein levels ( 30072576 29875488) Fruit consumption ( 32066663)
Interacting Genes		2 interacting genes: HDHD2 SERPINF2	12 interacting genes: ADGRB2 CFD CRMP1 DVL1 EPHB6 LUC7L2 MEOX2 MGST2 PIP5K1C SOD2 TARBP2 TRAPPC11
Entrez ID		1675	84064
HPRD ID		00600	13640
Ensembl ID		ENSG00000197766	ENSG00000167220
Uniprot IDs		A6XNE2 K7ERG9 P00746	Q9H0R4 V9HW73
PDB IDs		1BIO 1DFP 1DIC 1DST 1DSU 1FDP 1HFD 2XW9 2XWA 2XWB 4CBN 4CBO 4D9R 5FBE 5FBI 5FCK 5MT0 5MT4 5NAR 5NAT 5NAW 5NB6 5NB7 5NBA 5TCA 5TCC 6FTY 6FTZ 6FUG 6FUH 6FUI 6FUJ 6FUT 6QMR 6QMT 6VMJ 6VMK	3HLT
Enriched GO Terms of Interacting Partners?
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