HDHD2 and MGST2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
HPRD (two hybrid)

		HDHD2	MGST2
Description		haloacid dehalogenase like hydrolase domain containing 2	microsomal glutathione S-transferase 2
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GO Annotations	Cellular Component	Extracellular Exosome	Nuclear Envelope Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Phosphatase Activity Enzyme Binding Metal Ion Binding	Glutathione Transferase Activity Leukotriene-C4 Synthase Activity Glutathione Peroxidase Activity Protein Binding Enzyme Activator Activity Identical Protein Binding Glutathione Binding
	Biological Process	Biological_process Dephosphorylation	Lipid Metabolic Process Glutathione Biosynthetic Process Response To Organonitrogen Compound Leukotriene Biosynthetic Process Response To Lipopolysaccharide Membrane Lipid Catabolic Process Positive Regulation Of Inflammatory Response Regulation Of Catalytic Activity Cellular Oxidant Detoxification
Pathways			Glutathione conjugation Aflatoxin activation and detoxification
Drugs			Glutathione
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Fruit consumption ( 32066663)	Metabolite levels ( 23823483)
Interacting Genes		12 interacting genes: ADGRB2 CFD CRMP1 DVL1 EPHB6 LUC7L2 MEOX2 MGST2 PIP5K1C SOD2 TARBP2 TRAPPC11	23 interacting genes: ASIC1 BCL2L10 BCL2L2 C3orf52 CCL3L3 CLEC14A CREB3 CREB3L1 CTXN3 DNAJC30 GIMAP5 GJA8 GPX8 HDHD2 PLN PNKP SEC22A SEC22B SGCB STX8 TMEM167B TMEM207 VAMP3
Entrez ID		84064	4258
HPRD ID		13640	03436
Ensembl ID		ENSG00000167220	ENSG00000085871
Uniprot IDs		Q9H0R4 V9HW73	Q99735
PDB IDs		3HLT	6SSR 6SSS 6SSU 6SSW
Enriched GO Terms of Interacting Partners?
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