DCP2 and MX1

		DCP2	MX1
Description		decapping mRNA 2	MX dynamin like GTPase 1
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GO Annotations	Cellular Component	P-body Nucleoplasm Cytoplasm Cytosol RISC Complex Cell Junction Cytoplasmic Ribonucleoprotein Granule	Nucleus Cytoplasm Endoplasmic Reticulum Membrane Cytosol Microtubule Membrane Nuclear Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	5'-3' Exoribonuclease Activity Protein Binding Exoribonuclease Activity, Producing 5'-phosphomonoesters Manganese Ion Binding M7G(5')pppN Diphosphatase Activity Telomerase RNA Binding	GTPase Activity Protein Binding GTP Binding Microtubule Binding Identical Protein Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA MRNA Catabolic Process Negative Regulation Of Telomere Maintenance Via Telomerase Regulation Of MRNA Stability Exonucleolytic Catabolism Of Deadenylated MRNA Histone MRNA Catabolic Process RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Regulation Of Telomerase RNA Localization To Cajal Body	Apoptotic Process Defense Response Signal Transduction Response To Virus Response To Type I Interferon Negative Regulation Of Viral Genome Replication Innate Immune Response Defense Response To Virus Interleukin-27-mediated Signaling Pathway Antiviral Innate Immune Response
Pathways		ATF4 activates genes in response to endoplasmic reticulum stress mRNA decay by 5' to 3' exoribonuclease Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA KSRP (KHSRP) binds and destabilizes mRNA	ISG15 antiviral mechanism Interferon alpha/beta signaling
Drugs
Diseases
GWAS		Waist circumference ( 32902719) Worry/vulnerability (special factor of neuroticism) ( 30867560)
Interacting Genes		20 interacting genes: ACKR2 AGO1 AGO2 CYP27A1 DCP1A DCP1B EPB41L4A FEM1C KCNN2 MAPK3 MIR15B MTOR MX1 NAGK POLA2 PSMB1 TMED7 TRIM21 UPF1 UPF2	55 interacting genes: ACTB ADRM1 APP BLM BRD7 C7orf25 CAB39L CASP8AP2 CBX4 CCL16 CD5 CHD3 DAXX DCP2 EPM2AIP1 FANCA FXR1 GGPS1 GMEB1 GPC4 HMGXB4 KIF26B KLHL35 LRRC4B MCCD1 MX2 NDC80 NDUFV3 PDE9A PGRMC1 PIAS1 PIAS2 PLRG1 PRDX6 PSD3 PSG9 RELA SIAH1 SIRPA SLC25A3 SP100 TDG TRPC1 TRPC3 TRPC4 TRPC5 TRPC6 TRPC7 TUBA1A TUBB ZBTB16 ZCCHC12 ZFP36 ZNF251 ZNF623
Entrez ID		167227	4599
HPRD ID		13125	00919
Ensembl ID		ENSG00000172795	ENSG00000157601
Uniprot IDs		Q8IU60	P20591
PDB IDs		5MP0 5QOH 5QOI 5QOJ 5QOK 5QOL 5QOM 5QON 5QOO 5QOP 5QOQ 5QOR 5QOS 5QOT 5QOU 5QOV 5QOW 5QOX 5QOY 5QOZ 5QP0 5QP1 5QP2 5QP3 5QP4 5QP5 5QP6 5QP7 5QP8 5QP9 5QPA 5QPB 5QPC	3LJB 3SZR 3ZYS 4P4S 4P4T 4P4U 5GTM
Enriched GO Terms of Interacting Partners?
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