ZNF579 and SPARC

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		ZNF579	SPARC
Description		zinc finger protein 579	secreted protein acidic and cysteine rich
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Extracellular Region Basement Membrane Extracellular Space Cytoplasm Mitochondrion Plasma Membrane Cell Surface Nuclear Matrix Platelet Alpha Granule Platelet Alpha Granule Membrane Platelet Alpha Granule Lumen Intracellular Membrane-bounded Organelle Collagen-containing Extracellular Matrix Endocytic Vesicle Lumen Glutamatergic Synapse
	Molecular Function	DNA Binding RNA Binding Metal Ion Binding	Extracellular Matrix Structural Constituent Calcium Ion Binding Protein Binding Collagen Binding Extracellular Matrix Binding
	Biological Process		Ossification Negative Regulation Of Endothelial Cell Proliferation Heart Development Response To Gravity Response To Lead Ion Positive Regulation Of Endothelial Cell Migration Negative Regulation Of Angiogenesis Regulation Of Cell Morphogenesis Lung Development Response To Lipopolysaccharide Response To L-ascorbic Acid Response To Cytokine Wound Healing Response To Peptide Hormone Response To Ethanol Response To Cadmium Ion Inner Ear Development Anatomical Structure Development Regulation Of Synapse Organization Response To Glucocorticoid Response To CAMP Response To Calcium Ion
Pathways			Platelet degranulation Nuclear signaling by ERBB4 ECM proteoglycans Scavenging by Class H Receptors
Drugs			Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS		Periodontitis (Mean PAL) ( 24024966)	Stroke ( 32693751)
Interacting Genes		11 interacting genes: GADD45G ILK MAPK6 MEST NR4A1 OSGEP RASA1 RGS2 SF3B3 SPARC YAE1	24 interacting genes: COL13A1 COL1A1 COL1A2 COL2A1 COL3A1 COL5A1 CPEB2 CTSK FN1 HDAC5 HSPG2 PDGFA PDGFB PLAT PLG SDC2 TGFB1 TGM2 THBS1 TNC UBQLN1 VEGFA XRCC6 ZNF579
Entrez ID		163033	6678
HPRD ID		11730	01631
Ensembl ID		ENSG00000218891	ENSG00000113140
Uniprot IDs		Q8NAF0	P09486
PDB IDs			1BMO 1NUB 1SRA 2V53
Enriched GO Terms of Interacting Partners?
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