AARS1 and DHX38

		AARS1	DHX38
Description		alanyl-tRNA synthetase 1	DEAH-box helicase 38
Image
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Cytosol Membrane Extracellular Exosome	Intracellular Anatomical Structure Nucleus Nucleoplasm Spliceosomal Complex Membrane Catalytic Step 2 Spliceosome
	Molecular Function	TRNA Binding Aminoacyl-tRNA Editing Activity Ser-tRNA(Ala) Hydrolase Activity Alanine-tRNA Ligase Activity ATP Binding Zinc Ion Binding Amino Acid Binding Translation Regulator Activity	RNA Binding RNA Helicase Activity Protein Binding ATP Binding ATP Hydrolysis Activity
	Biological Process	TRNA Modification TRNA Aminoacylation For Protein Translation Alanyl-tRNA Aminoacylation TRNA Processing Cerebellar Purkinje Cell Layer Development Negative Regulation Of Neuron Apoptotic Process Neuromuscular Process Controlling Balance Aminoacyl-tRNA Metabolism Involved In Translational Fidelity Regulation Of Cytoplasmic Translational Fidelity	MRNA Splicing, Via Spliceosome
Pathways		Cytosolic tRNA aminoacylation	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs		Alanine
Diseases
GWAS			Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Blood protein levels ( 28240269 23696881) Cholesterol, total ( 25961943 20686565) Coronary artery disease ( 29212778) Depression ( 29700475) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) LDL cholesterol ( 25961943 20686565) Medication use (HMG CoA reductase inhibitors) ( 31015401) Metabolite levels ( 22916037) Red blood cell count ( 32888494) Serum metabolite levels (CMS) ( 31636271) Urate levels ( 31578528)
Interacting Genes		5 interacting genes: CDC42 DHX38 EEF1B2 LINC01554 SUMO2	16 interacting genes: AARS1 ACTL7B BCO1 CDC40 CMTM3 CSNK2A1 CTCF E2F4 MFAP1 NDRG4 NOL3 PPP4C SNRNP200 TNFRSF4 U2AF1 WBP4
Entrez ID		16	9785
HPRD ID		03042	05720
Ensembl ID		ENSG00000090861	ENSG00000140829
Uniprot IDs		P49588	Q92620
PDB IDs		4XEM 4XEO 5KNN 5T5S 5T76 5V59	5YZG 6ZYM 7A5P
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?