DHX38 and CMTM3

		DHX38	CMTM3
Description		DEAH-box helicase 38	CKLF like MARVEL transmembrane domain containing 3
Image			No pdb structure
GO Annotations	Cellular Component	Intracellular Anatomical Structure Nucleus Nucleoplasm Spliceosomal Complex Membrane Catalytic Step 2 Spliceosome	Extracellular Space Cytosol Integral Component Of Membrane Cytoplasmic Vesicle Nuclear Membrane
	Molecular Function	RNA Binding RNA Helicase Activity Protein Binding ATP Binding ATP Hydrolysis Activity	Cytokine Activity Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome	Blastocyst Hatching Chemotaxis Signal Transduction Positive Regulation Of B Cell Receptor Signaling Pathway
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Blood protein levels ( 28240269 23696881) Cholesterol, total ( 25961943 20686565) Coronary artery disease ( 29212778) Depression ( 29700475) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) LDL cholesterol ( 25961943 20686565) Medication use (HMG CoA reductase inhibitors) ( 31015401) Metabolite levels ( 22916037) Red blood cell count ( 32888494) Serum metabolite levels (CMS) ( 31636271) Urate levels ( 31578528)
Interacting Genes		16 interacting genes: AARS1 ACTL7B BCO1 CDC40 CMTM3 CSNK2A1 CTCF E2F4 MFAP1 NDRG4 NOL3 PPP4C SNRNP200 TNFRSF4 U2AF1 WBP4	32 interacting genes: APOA5 APP AQP6 ARL13B BLNK BTK CREB3L1 DHX38 ELOVL4 GJB1 GPR35 HSD17B11 IKBIP IL10RA LEUTX LMNA LRRC59 MAPK1 MEST MFSD14B MOB1A MOB3C MRM1 NDRG4 RABAC1 REEP4 RETREG3 SLC10A1 SPP1 STMN4 SYT2 VEZT
Entrez ID		9785	123920
HPRD ID		05720	16259
Ensembl ID		ENSG00000140829	ENSG00000140931
Uniprot IDs		Q92620	A0A024R6Y8 H3BUD5 Q96MX0
PDB IDs		5YZG 6ZYM 7A5P
Enriched GO Terms of Interacting Partners?
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