CYB561 and VAPA

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CYB561	VAPA
Description		cytochrome b561	VAMP associated protein A
Image		No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Integral Component Of Membrane Chromaffin Granule Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Bicellular Tight Junction Microtubule Cytoskeleton Integral Component Of Membrane Nuclear Membrane Vesicle Azurophil Granule Membrane Perinuclear Region Of Cytoplasm Endoplasmic Reticulum Exit Site
	Molecular Function	Protein Binding Oxidoreductase Activity Metal Ion Binding Transmembrane Monodehydroascorbate Reductase Activity	Protein Binding Microtubule Binding Protein Domain Specific Binding FFAT Motif Binding Cadherin Binding Protein Heterodimerization Activity
	Biological Process	Cellular Iron Ion Homeostasis Electron Transport Chain Ascorbate Homeostasis	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Endoplasmic Reticulum Organization Cell Death Neuron Projection Development Protein Folding In Endoplasmic Reticulum Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation By Host Of Viral Release From Host Cell Negative Regulation By Host Of Viral Genome Replication Positive Regulation By Host Of Viral Genome Replication Membrane Fusion Protein Localization To Endoplasmic Reticulum COPII-coated Vesicle Budding
Pathways			Sphingolipid de novo biosynthesis Neutrophil degranulation Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases
GWAS		Cerebrospinal fluid levels of Alzheimer's disease-related proteins ( 25340798) Diastolic blood pressure ( 28739976)	Diverticular disease ( 30177863) FEV1 ( 30804560) Heel bone mineral density ( 30598549) Lung function (FEV1/FVC) ( 30804560) Metabolite levels ( 23823483) Peak expiratory flow ( 30804560) Pulmonary function (smoking interaction) ( 23284291)
Interacting Genes		60 interacting genes: ANKRD46 AQP6 BEST2 BET1 BIK BNIP1 CD79A CDIPT CLDN9 CMTM2 CREB3 DARS2 EBP EDA EFNA5 EHHADH ERG28 ERGIC3 FKBP8 GGT7 GIMAP5 GOSR2 GPR152 GPX8 HMOX1 LHFPL5 LMNA LPAR3 NCOA1 OPRM1 ORMDL2 PLP2 REEP6 RNF5 SCD SEC22A SERP2 SLC19A3 SLC35C2 SLC38A7 SLC39A1 SLC39A2 SMIM1 SSMEM1 STX3 SYNJ2BP TM4SF18 TMEM11 TMEM128 TMEM14B TMEM179B TMEM242 TMEM65 TMPPE TREX1 TSNARE1 UBE2J1 VAPA VAPB ZDHHC7	37 interacting genes: ADGRG7 ADRB2 APOD AQP6 CACNG1 CD79A CYB561 CYBRD1 EBAG9 EBP EGFR ERBB2 GKN1 HSD17B13 JAGN1 KCNB1 LEPROTL1 NSF OPRM1 OSBP PGRMC2 RETREG3 RMDN2 SCN3B SEC11C SIK1 SLC16A7 SLC35B1 TMEM229B TMEM35A TMEM86B TMIE TMX2 USP20 VAMP1 VAMP2 ZBTB22
Entrez ID		1534	9218
HPRD ID		02485	09299
Ensembl ID		ENSG00000008283	ENSG00000101558
Uniprot IDs		B3KTA1 J3QRH5 P49447	Q9P0L0
PDB IDs			2RR3 6TQR
Enriched GO Terms of Interacting Partners?
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