CTNND2 and CTTN

Number of citations of the paper that reports this interaction (PubMedID 12835311)
48

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		CTNND2	CTTN
Description		catenin delta 2	cortactin
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Adherens Junction Postsynaptic Density Dendrite Perikaryon	Ruffle Podosome Cytoplasm Golgi Apparatus Cytosol Cytoskeleton Actin Filament Plasma Membrane Clathrin-coated Pit Focal Adhesion Cell Cortex Lamellipodium Growth Cone Site Of Polarized Growth Cortical Cytoskeleton Cortical Actin Cytoskeleton Dendritic Spine Intracellular Membrane-bounded Organelle Mitotic Spindle Midzone
	Molecular Function	Protein Binding Beta-catenin Binding Cadherin Binding	Protein Binding Profilin Binding Cadherin Binding Actin Filament Binding
	Biological Process	Cell-cell Junction Assembly Cell Adhesion Signal Transduction Wnt Signaling Pathway Synapse Organization Regulation Of Canonical Wnt Signaling Pathway Dendritic Spine Morphogenesis Cell-cell Adhesion	Intracellular Protein Transport Receptor-mediated Endocytosis Substrate-dependent Cell Migration, Cell Extension Actin Filament Polymerization Regulation Of Axon Extension Regulation Of Actin Filament Polymerization Positive Regulation Of Actin Filament Polymerization Actin Cytoskeleton Reorganization Positive Regulation Of Smooth Muscle Contraction Focal Adhesion Assembly Neuron Projection Morphogenesis Cell Motility Dendritic Spine Maintenance Lamellipodium Organization Regulation Of Autophagy Of Mitochondrion Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways			RHO GTPases activate PAKs Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Cannabis dependence symptom count ( 27028160) Clostridioides difficle infection ( 33841421) Cognitive performance (processing speed) ( 31598132) Common carotid intima-media thickness in HIV infection ( 29206233) Corneal astigmatism ( 30306274) Facial emotion recognition ( 28608620) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Lewy body disease ( 25188341) Macular thickness ( 30535121) Myopia (pathological) ( 21095009) Pulse pressure ( 27841878) Refractive error ( 32231278) Response to antidepressants (symptom improvement) ( 29160301) Sensorimotor dexterity ( 31596458) Serum docosahexaenoic fatty acid concentration in metabolic syndrome ( 31991592) Systolic blood pressure ( 27841878) Very long-chain saturated fatty acid levels (fatty acid 20:0) ( 25378659)
Interacting Genes		21 interacting genes: ABL1 ATN1 CDH1 CDH2 CLK1 CTNNB1 CTTN DNAH5 ERBIN FYN LCK LNX1 LRRC7 MAGI2 NUDT21 PDZD2 PSEN1 PSEN2 PTGER4 SPHK1 TTR	44 interacting genes: ACD ACTA1 ACTG1 ACTR3 ANKZF1 ARHGAP17 ARHGAP8 CASP3 CD2AP CD5 CHD3 CTNND1 CTNND2 CTTNBP2 DNM1 DNM2 EGFR FER FGD1 GRB2 HAX1 HDAC6 HIP1R KCNA2 KEAP1 MET MYLK NHSL2 RPL9 SDC3 SH3BP2 SHANK2 SHANK3 SIRT1 SMURF1 SPRR2A SRC SYK TINF2 TJP1 TNK2 TRIM15 WASL WIPF1
Entrez ID		1501	2017
HPRD ID		09181	01268
Ensembl ID		ENSG00000169862	ENSG00000085733
Uniprot IDs		B4DJU1 B4DRK2 E7EPC8 Q9UQB3	A0A024R5M3 Q14247 Q53HG7
PDB IDs			1X69 2D1X
Enriched GO Terms of Interacting Partners?
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