CTNNA2 and TOMM70

		CTNNA2	TOMM70
Description		catenin alpha 2	translocase of outer mitochondrial membrane 70
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Adherens Junction Actin Cytoskeleton Catenin Complex Axon	Mitochondrion Mitochondrial Outer Membrane Mitochondrial Outer Membrane Translocase Complex Membrane Integral Component Of Membrane Extracellular Exosome
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Beta-catenin Binding Cadherin Binding Actin Filament Binding	Protein Binding Protein Transmembrane Transporter Activity Mitochondrion Targeting Sequence Binding
	Biological Process	Cytoskeleton Organization Axonogenesis Regulation Of Neuron Projection Development Cell Migration Radial Glia Guided Migration Of Purkinje Cell Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Dendrite Morphogenesis Brain Morphogenesis Regulation Of Synapse Structural Plasticity Prepulse Inhibition Cell-cell Adhesion Regulation Of Neuron Migration	Activation Of Innate Immune Response Positive Regulation Of Defense Response To Virus By Host Protein Targeting To Mitochondrion Protein Import Into Mitochondrial Matrix Positive Regulation Of Interferon-beta Production Regulation Of Apoptotic Process Protein Insertion Into Mitochondrial Inner Membrane Cellular Response To Virus
Pathways		Myogenesis Myogenesis	Mitochondrial protein import DDX58/IFIH1-mediated induction of interferon-alpha/beta PINK1-PRKN Mediated Mitophagy Ub-specific processing proteases
Drugs
Diseases
GWAS		Adult body size ( 32376654) Alcohol consumption ( 28937693) Alcohol dependence or heroin dependence or methamphetamine dependence ( 31462767) Alzheimer's disease (cognitive decline) ( 23535033) Bipolar disorder ( 19416921) Body mass index ( 26426971 25673413) Bone mineral density (femoral neck) ( 26911590) Breast cancer ( 25824743) Cerebral microbleeds ( 31209788) Cerebrospinal fluid clusterin levels ( 26545630) Cleft palate ( 30452639) Cognitive function ( 25644384) Contrast sensitivity ( 24152035) Cooked vegetable consumption ( 32066663) Fish- and plant-related diet ( 32066663) Gut microbiota relative abundance (Bacteroides) ( 33208821) LDL cholesterol levels in HIV infection ( 33109212) Mild influenza (H1N1) infection ( 26379185) Multisite chronic pain ( 33830993 31194737) Orthostatic hypotension ( 24124408) Proportion of activated microglia (inferior temporal cortex) ( 30679421) Protein quantitative trait loci ( 18464913) Raw vegetable consumption ( 32066663) Refractive error ( 32231278) Response to cytadine analogues (cytosine arabinoside) ( 24483146) Response to lurasidone in schizophrenia ( 29730043) Schizophrenia (MTAG) ( 32107650) Survival in pancreatic cancer ( 28470677)
Interacting Genes		3 interacting genes: CTNNBIP1 PTPN14 TOMM70	18 interacting genes: CTNNA2 DCBLD2 FOXC1 HSP90AA1 HSPA1A HSPA1B HSPB1 IRF3 KIF2C NIT2 OGT OR5K4 PRKN PSAP SNAPIN TBC1D23 TFG TMEM45A
Entrez ID		1496	9868
HPRD ID		00228	16194
Ensembl ID		ENSG00000066032	ENSG00000154174
Uniprot IDs		F6KRI5 P26232 Q49AD3	O94826
PDB IDs		6DUW	7KDT
Enriched GO Terms of Interacting Partners?
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