MOB3C and IKZF4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MOB3C	IKZF4
Description		MOB kinase activator 3C	IKAROS family zinc finger 4
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus Nucleoplasm Nuclear Body Protein-containing Complex
	Molecular Function	Protein Binding Protein Kinase Activator Activity Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Protein Domain Specific Binding
	Biological Process	Positive Regulation Of Protein Phosphorylation Signal Transduction	Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription, DNA-templated Protein Homooligomerization
Pathways
Drugs
Diseases
GWAS		Chronic kidney disease ( 30226566) Hypertension ( 30226566)	Age at first birth ( 34211149) Allergic disease (asthma, hay fever or eczema) ( 29083406 29785011) Alopecia areata ( 20596022 25608926) Anorexia nervosa ( 28494655) Asthma ( 21804548 31959851 32700739 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Autoimmune traits (pleiotropy) ( 30572963) Brain morphology (MOSTest) ( 32665545) Cognitive ability (MTAG) ( 29186694) Cognitive function ( 25644384) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Neutrophil percentage of granulocytes ( 27863252) Refractive error ( 32231278) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258) Type 1 diabetes ( 21829393 25751624 18198356) Vitiligo ( 27723757 22561518)
Interacting Genes		18 interacting genes: APP CMTM3 FAM118A FBXO7 IKZF4 KANK2 KRT40 LATS1 LATS2 NT5C2 PCYT1A PICK1 PTPN21 SIAH1 TDO2 TFCP2 TNIP1 ZBTB10	20 interacting genes: CDC7 CHD4 CSNK1D FHL2 FOXP3 HDAC2 IKZF1 IKZF2 IKZF3 IKZF5 MCRS1 MOB1A MOB3C NFKBIA NRG1 SIN3A SIN3B TCAF1 TCEA2 TXK
Entrez ID		148932	64375
HPRD ID		17584	05874
Ensembl ID		ENSG00000142961	ENSG00000123411
Uniprot IDs		Q70IA8 X6R3L3	Q9H2S9
PDB IDs			2MA7
Enriched GO Terms of Interacting Partners?
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