CSTF1 and MIRLET7I

Number of citations of the paper that reports this interaction (PubMedID 28431233)
92

Data Source:
BioGRID (unspecified method)

		CSTF1	MIRLET7I
Description		cleavage stimulation factor subunit 1	microRNA let-7i
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm MRNA Cleavage Stimulating Factor Complex	Extracellular Space Nucleus Cytoplasm Extracellular Vesicle
	Molecular Function	RNA Binding Protein Binding	RNA Polymerase II Complex Binding MRNA 3'-UTR Binding Sequence-specific Single Stranded DNA Binding MRNA Binding Involved In Posttranscriptional Gene Silencing
	Biological Process	MRNA 3'-end Processing	Negative Regulation Of Gene Expression Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Defense Response To Protozoan Positive Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly Positive Regulation Of Transcription By RNA Polymerase II
Pathways		mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS		Cognitive decline (age-related) ( 28078323)
Interacting Genes		12 interacting genes: BARD1 BRCA1 CSTF3 H2AC20 MIR140 MIR206 MIR92A2 MIRLET7A3 MIRLET7I POLR2A TOLLIP VCP	113 interacting genes: AGO2 AIMP1 AIMP2 APOBEC3B AQR ATXN2L C1QBP CDC5L CELF1 CELF2 CHERP CPSF1 CRTAP CSTF1 CSTF3 DARS1 DDX1 DDX21 DDX23 DDX3X DHX36 DHX37 EIF2AK2 ELAVL1 EPRS1 ERAL1 ESRP1 FAM98A FIP1L1 FUS G3BP2 GRSF1 HARS2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI1 MSI2 MYEF2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 P3H1 PAXBP1 PDCD11 PLOD1 PLRG1 PTBP1 PUF60 PUM1 PURA PURB QARS1 RARS1 RBFOX2 RBM10 RBM14 RBM17 RBM4 RBM4B RBM5 RTCA RTCB SF3A1 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 SUGP2 SYMPK SYNCRIP TAF15 TRA2A TRA2B TUT4 TUT7 U2SURP UPF1 UTP20 XAB2 YBX1 YBX2 YBX3 ZFR ZNF106 ZNF346
Entrez ID		1477	406891
HPRD ID		02653
Ensembl ID		ENSG00000101138	ENSG00000199179
Uniprot IDs		Q05048
PDB IDs		6B3X
Enriched GO Terms of Interacting Partners?
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