TMEM199 and CD300A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TMEM199	CD300A
Description		transmembrane protein 199	CD300a molecule
Image		No pdb structure
GO Annotations	Cellular Component	Lysosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endomembrane System Integral Component Of Membrane Vacuolar Proton-transporting V-type ATPase Complex COPI-coated Vesicle Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Plasma Membrane Membrane Integral Component Of Membrane Extracellular Exosome Tertiary Granule Membrane Ficolin-1-rich Granule Membrane
	Molecular Function	Protein Binding	Phosphatidylserine Binding Transmembrane Signaling Receptor Activity Protein Binding Phosphatidylethanolamine Binding Signaling Receptor Activity
	Biological Process	Cellular Iron Ion Homeostasis Lysosomal Lumen Acidification Cellular Response To Increased Oxygen Levels Vacuolar Proton-transporting V-type ATPase Complex Assembly Lysosomal Protein Catabolic Process	Immune System Process Cell Adhesion Negative Regulation Of B Cell Proliferation Positive Regulation Of Phosphoprotein Phosphatase Activity Negative Regulation Of Mast Cell Activation Involved In Immune Response Negative Regulation Of MyD88-dependent Toll-like Receptor Signaling Pathway Negative Regulation Of Mast Cell Degranulation Negative Regulation Of MAP Kinase Activity Negative Regulation Of Fibroblast Proliferation Regulation Of T Cell Receptor Signaling Pathway Negative Regulation Of B Cell Receptor Signaling Pathway Negative Regulation Of NK T Cell Activation Negative Regulation Of Phagocytosis, Engulfment Negative Regulation Of Neutrophil Activation Negative Regulation Of Eosinophil Activation Negative Regulation Of Activation Of Janus Kinase Activity Negative Regulation Of Eosinophil Migration
Pathways			Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Neutrophil degranulation
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Apolipoprotein B levels ( 32203549) Blood protein levels ( 29875488) HDL cholesterol levels ( 32203549) LDL cholesterol levels ( 32203549) Low density lipoprotein cholesterol levels ( 32154731) Osteoprotegerin levels ( 25080503) Triglyceride levels ( 32203549)	Blood protein levels ( 30072576 29875488) Neurological blood protein biomarker levels ( 31320639)
Interacting Genes		17 interacting genes: AQP6 BIK CCR2 CD300A EBP ELOVL4 ERLIN1 IFNGR2 JAGN1 KASH5 LMNA REEP4 SLC10A4 STX1A STX4 TIMMDC1 TMEM14B	7 interacting genes: KRT38 KRTAP10-3 SEC22A SLC9A3R1 TMEM199 TMEM218 TMEM60
Entrez ID		147007	11314
HPRD ID		12679	09492
Ensembl ID		ENSG00000244045	ENSG00000167851
Uniprot IDs		Q8N511	J3QKQ4 Q9UGN4
PDB IDs			2Q87
Enriched GO Terms of Interacting Partners?
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