RAD9B and RAD17

Number of citations of the paper that reports this interaction (PubMedID 14611806)
10

Data Source:
HPRD (in vitro, in vivo)

		RAD9B	RAD17
Description		RAD9 checkpoint clamp component B	RAD17 checkpoint clamp loader component
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Checkpoint Clamp Complex	Chromosome, Telomeric Region Nucleus Nucleoplasm Nucleolus Rad17 RFC-like Complex
	Molecular Function	Protein Binding	Chromatin Binding DNA Clamp Loader Activity Protein Binding ATP Binding
	Biological Process	DNA Replication Checkpoint Signaling DNA Repair Mitotic Intra-S DNA Damage Checkpoint Signaling Cellular Response To Ionizing Radiation	DNA Replication Checkpoint Signaling DNA Damage Checkpoint Signaling DNA Repair Cellular Response To DNA Damage Stimulus Negative Regulation Of DNA Replication Mitotic Intra-S DNA Damage Checkpoint Signaling Mitotic DNA Replication Checkpoint Signaling Regulation Of Phosphorylation
Pathways		Activation of ATR in response to replication stress HDR through Single Strand Annealing (SSA) Processing of DNA double-strand break ends Presynaptic phase of homologous DNA pairing and strand exchange Regulation of TP53 Activity through Phosphorylation G2/M DNA damage checkpoint	Activation of ATR in response to replication stress HDR through Single Strand Annealing (SSA) Processing of DNA double-strand break ends Presynaptic phase of homologous DNA pairing and strand exchange Regulation of TP53 Activity through Phosphorylation G2/M DNA damage checkpoint
Drugs
Diseases
GWAS			Blood urea nitrogen levels ( 31152163)
Interacting Genes		5 interacting genes: HUS1 HUS1B RAD1 RAD17 RAD9A	16 interacting genes: ATM ATR F2RL1 HUS1 MCM7 POLE PRKDC PRMT6 RAD1 RAD9A RAD9B RFC2 RFC3 RFC4 SNU13 USP20
Entrez ID		144715	5884
HPRD ID		12221	09124
Ensembl ID		ENSG00000151164	ENSG00000152942
Uniprot IDs		A0A024RBJ5 A0A024RBN9 B4DX60 B4DYM6 J3KPN7 Q6WBX8	O75943
PDB IDs
Enriched GO Terms of Interacting Partners?
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