RAD17

Description		RAD17 checkpoint clamp loader component
Image		No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Nucleus Nucleoplasm Nucleolus Rad17 RFC-like Complex
	Molecular Function	Chromatin Binding DNA Clamp Loader Activity Protein Binding ATP Binding
	Biological Process	DNA Replication Checkpoint Signaling DNA Damage Checkpoint Signaling DNA Repair Cellular Response To DNA Damage Stimulus Negative Regulation Of DNA Replication Mitotic Intra-S DNA Damage Checkpoint Signaling Mitotic DNA Replication Checkpoint Signaling Regulation Of Phosphorylation
Pathways		Activation of ATR in response to replication stress HDR through Single Strand Annealing (SSA) Processing of DNA double-strand break ends Presynaptic phase of homologous DNA pairing and strand exchange Regulation of TP53 Activity through Phosphorylation G2/M DNA damage checkpoint
Drugs
Diseases
GWAS		Blood urea nitrogen levels ( 31152163)
Interacting Genes		16 interacting genes: ATM ATR F2RL1 HUS1 MCM7 POLE PRKDC PRMT6 RAD1 RAD9A RAD9B RFC2 RFC3 RFC4 SNU13 USP20
Entrez ID		5884
HPRD ID		09124
Ensembl ID		ENSG00000152942
Uniprot IDs		O75943
PDB IDs
Enriched GO Terms of Interacting Partners?
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