CSF3 and PARVG

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CSF3	PARVG
Description		colony stimulating factor 3	parvin gamma
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Lysosomal Lumen Endocytic Vesicle Lumen	Cytoplasm Cytoskeleton Plasma Membrane Focal Adhesion Actin Cytoskeleton
	Molecular Function	Cytokine Activity Granulocyte Colony-stimulating Factor Receptor Binding Growth Factor Activity Enzyme Binding	Actin Binding Protein Binding
	Biological Process	Immune Response Multicellular Organism Development Positive Regulation Of Cell Population Proliferation Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Cytokine-mediated Signaling Pathway Positive Regulation Of Actin Filament Polymerization Granulocyte Differentiation Positive Regulation Of Protein Binding Positive Regulation Of Peptidyl-serine Phosphorylation Response To Ethanol Positive Regulation Of Myeloid Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Protein Kinase B Signaling Cellular Response To Lipopolysaccharide Cellular Response To Cytokine Stimulus Negative Regulation Of Neuron Death Positive Regulation Of Actin Cytoskeleton Reorganization	Cell-matrix Adhesion Establishment Or Maintenance Of Cell Polarity Cell Projection Assembly Actin Cytoskeleton Reorganization Substrate Adhesion-dependent Cell Spreading
Pathways		Other interleukin signaling Interleukin-10 signaling Signaling by CSF3 (G-CSF) Signaling by CSF3 (G-CSF) Inactivation of CSF3 (G-CSF) signaling Inactivation of CSF3 (G-CSF) signaling
Drugs
Diseases
GWAS		Asthma ( 31619474) Bipolar disorder ( 31043756) Composite immunoglobulin trait (IgA x IgG) ( 28628107) Creatine kinase levels ( 29403010) Granulocyte count ( 27863252) Granulocyte percentage of myeloid white cells ( 27863252) Lymphocyte percentage of white cells ( 32888494 27863252) Mitochondrial DNA copy number ( 30704525) Myeloid white cell count ( 27863252) Neutrophil count ( 25096241 20172861 32888494 27863252) Neutrophil percentage of white cells ( 32888494 27863252) Rheumatoid arthritis ( 30423114 24390342) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 29403010 32888494 20139978 27863252 21738480 28158719) White blood cell count (neutrophil) ( 28158719) White blood cell types ( 21738478)	Fasting glucose ( 33381925) Metabolite levels ( 23823483) Survival in colon cancer ( 25866641)
Interacting Genes		9 interacting genes: CDK2 CSF3R ELANE HDAC6 NOS2 NQO2 PARVG SLFN11 TBX3	33 interacting genes: ALX4 ANTKMT APP CDHR3 CDSN CFAP53 CSF3 DDIT4L FOSL1 GADD45A HOMEZ ILK KCTD7 KLHL32 LHX3 LNX2 MEOX1 MEOX2 NBPF22P NBPF6 NDEL1 PDLIM7 POLR2G POU6F2 REL SERTAD2 TLE5 TRIB2 TRIM54 TSGA10IP USHBP1 ZNF426 ZNF677
Entrez ID		1440	64098
HPRD ID		00736	16285
Ensembl ID		ENSG00000108342	ENSG00000138964
Uniprot IDs		P09919 Q6FH65 Q8N4W3	A0A024R4U4 Q9HBI0
PDB IDs		1CD9 1GNC 1PGR 1RHG 2D9Q 5GW9 5ZO6
Enriched GO Terms of Interacting Partners?
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