CSF3 and NQO2

		CSF3	NQO2
Description		colony stimulating factor 3	N-ribosyldihydronicotinamide:quinone reductase 2
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Lysosomal Lumen Endocytic Vesicle Lumen	Nucleoplasm Cytosol Extracellular Exosome
	Molecular Function	Cytokine Activity Granulocyte Colony-stimulating Factor Receptor Binding Growth Factor Activity Enzyme Binding	Dihydronicotinamide Riboside Quinone Reductase Activity NAD(P)H Dehydrogenase (quinone) Activity Protein Binding Zinc Ion Binding Electron Transfer Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On Other Nitrogenous Compounds As Donors Chloride Ion Binding Protein Homodimerization Activity FAD Binding Melatonin Binding Resveratrol Binding
	Biological Process	Immune Response Multicellular Organism Development Positive Regulation Of Cell Population Proliferation Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Cytokine-mediated Signaling Pathway Positive Regulation Of Actin Filament Polymerization Granulocyte Differentiation Positive Regulation Of Protein Binding Positive Regulation Of Peptidyl-serine Phosphorylation Response To Ethanol Positive Regulation Of Myeloid Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Protein Kinase B Signaling Cellular Response To Lipopolysaccharide Cellular Response To Cytokine Stimulus Negative Regulation Of Neuron Death Positive Regulation Of Actin Cytoskeleton Reorganization	Memory Electron Transport Chain Positive Regulation Of Neuron Apoptotic Process Positive Regulation Of ERK1 And ERK2 Cascade Quinone Catabolic Process Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Positive Regulation Of Reactive Oxygen Species Metabolic Process
Pathways		Other interleukin signaling Interleukin-10 signaling Signaling by CSF3 (G-CSF) Signaling by CSF3 (G-CSF) Inactivation of CSF3 (G-CSF) signaling Inactivation of CSF3 (G-CSF) signaling	Phase I - Functionalization of compounds
Drugs			NADH Menadione Melatonin Primaquine Resveratrol Flavin adenine dinucleotide 10-Propargyl-5,8-Dideazafolic Acid Quercetin Tretazicar (3S)-3-hydroxy-1-methyl-2,3-dihydro-1H-indole-5,6-dione N-[2-(2-iodo-5-methoxy-1H-indol-3-yl)ethyl]acetamide 5,8-dimethoxy-1,4-dimethylquinolin-2(1H)-one Casimiroin
Diseases
GWAS		Asthma ( 31619474) Bipolar disorder ( 31043756) Composite immunoglobulin trait (IgA x IgG) ( 28628107) Creatine kinase levels ( 29403010) Granulocyte count ( 27863252) Granulocyte percentage of myeloid white cells ( 27863252) Lymphocyte percentage of white cells ( 32888494 27863252) Mitochondrial DNA copy number ( 30704525) Myeloid white cell count ( 27863252) Neutrophil count ( 25096241 20172861 32888494 27863252) Neutrophil percentage of white cells ( 32888494 27863252) Rheumatoid arthritis ( 30423114 24390342) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 29403010 32888494 20139978 27863252 21738480 28158719) White blood cell count (neutrophil) ( 28158719) White blood cell types ( 21738478)	Blood protein levels ( 30072576 29875488) Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		9 interacting genes: CDK2 CSF3R ELANE HDAC6 NOS2 NQO2 PARVG SLFN11 TBX3	10 interacting genes: CSF3 DDIT4L DGCR6 DRD2 EFHC1 GORASP2 IL32 LRRC7 MTCH1 SPG21
Entrez ID		1440	4835
HPRD ID		00736	01190
Ensembl ID		ENSG00000108342	ENSG00000124588
Uniprot IDs		P09919 Q6FH65 Q8N4W3	B3KPX6 P16083 Q5TD07
PDB IDs		1CD9 1GNC 1PGR 1RHG 2D9Q 5GW9 5ZO6	1QR2 1SG0 1XI2 1ZX1 2BZS 2QMY 2QMZ 2QR2 2QWX 2QX4 2QX6 2QX8 2QX9 3FW1 3G5M 3GAM 3NFR 3NHF 3NHJ 3NHK 3NHL 3NHP 3NHR 3NHS 3NHU 3NHW 3NHY 3O2N 3O73 3OVM 3OWH 3OWX 3OX1 3OX2 3OX3 3TE7 3TEM 3TZB 3UXE 3UXH 4FGJ 4FGK 4FGL 4GQI 4GR9 4QOD 4QOE 4QOF 4QOG 4QOH 4QOI 4QOJ 4U7F 4U7G 4U7H 4XDG 4XDH 4ZVK 4ZVL 4ZVM 4ZVN 5BUC 5LBT 5LBU 5LBW 5LBY 5LBZ
Enriched GO Terms of Interacting Partners?
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