MPP7 and MYSM1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MPP7	MYSM1
Description		MAGUK p55 scaffold protein 7	Myb like, SWIRM and MPN domains 1
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GO Annotations	Cellular Component	Nucleoplasm Adherens Junction Bicellular Tight Junction Cell Cortex Lateral Plasma Membrane Cell Junction MPP7-DLG1-LIN7 Complex	Nucleus Nucleoplasm Nucleolus Cytoplasm Protein-containing Complex
	Molecular Function	Protein Binding Protein Domain Specific Binding Signaling Adaptor Activity Cadherin Binding Molecular Adaptor Activity	DNA Binding Transcription Coactivator Activity Thiol-dependent Deubiquitinase Protein Binding Metallopeptidase Activity Histone Binding Metal Ion Binding Isopeptidase Activity
	Biological Process	Establishment Of Cell Polarity Positive Regulation Of Protein-containing Complex Assembly Bicellular Tight Junction Assembly Protein Localization To Adherens Junction	Immune System Process Chromatin Remodeling Monoubiquitinated Histone H2A Deubiquitination Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Hemopoiesis
Pathways		RAC1 GTPase cycle RAC2 GTPase cycle RHOQ GTPase cycle RHOG GTPase cycle RHOJ GTPase cycle RAC3 GTPase cycle	Metalloprotease DUBs
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Bone mineral density ( 24249740) Bone mineral density (paediatric, skull) ( 24945404) Diverticular disease ( 30177863) Glaucoma (primary open-angle) ( 27001270) Heel bone mineral density ( 30598549 28869591) Hippocampal volume ( 21116278) Lumbar spine bone mineral density ( 29499414 22504420) Macular thickness ( 30535121) Obesity-related traits ( 23251661) Psychosis and Alzheimer's disease ( 22005930)	Diabetic retinopathy ( 21310492) Metabolite levels ( 23823483) Nickel levels ( 26025379) Night sleep phenotypes ( 27126917)
Interacting Genes		7 interacting genes: DLGAP4 HSBP1 LIN7A LIN7B LIN7C MYSM1 TRIM5	4 interacting genes: H2AC20 HOOK1 MPP7 STING1
Entrez ID		143098	114803
HPRD ID		14733	13903
Ensembl ID		ENSG00000150054	ENSG00000162601
Uniprot IDs		Q5T2T1	Q5VVJ2
PDB IDs		3LRA 3O46	2CU7 2DCE
Enriched GO Terms of Interacting Partners?
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