DYNLL2 and DLGAP1

Number of citations of the paper that reports this interaction (PubMedID 10844022)
81

Data Source:
BioGRID (pull down)
HPRD (two hybrid, in vitro)

		DYNLL2	DLGAP1
Description		dynein light chain LC8-type 2	DLG associated protein 1
Image
GO Annotations	Cellular Component	Nucleus Centrosome Cytosol Cytoplasmic Dynein Complex Microtubule Plasma Membrane Cilium Postsynaptic Density Membrane Dynein Complex Myosin V Complex Ciliary Tip 9+0 Non-motile Cilium Postsynapse Glutamatergic Synapse	Cellular_component Plasma Membrane Postsynaptic Density Glutamatergic Synapse Postsynaptic Specialization
	Molecular Function	Protein Binding Identical Protein Binding Protein-containing Complex Binding Dynein Intermediate Chain Binding Dynein Light Intermediate Chain Binding Scaffold Protein Binding	Protein Binding Protein-containing Complex Binding Molecular Adaptor Activity
	Biological Process	Microtubule-based Process Cilium Assembly	Chemical Synaptic Transmission Regulation Of Postsynaptic Neurotransmitter Receptor Activity
Pathways		Activation of BMF and translocation to mitochondria Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Macroautophagy MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand Intraflagellar transport RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase HCMV Early Events Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation	Neurexins and neuroligins Neurexins and neuroligins
Drugs
Diseases
GWAS		Blood protein levels ( 30072576)	Alanine aminotransferase levels ( 31219225) Body fat mass ( 28552196) Cardiac Troponin-T levels ( 23247143) Eating disorders ( 22911880) Economic and political preferences (time) ( 22566634) Erythrocyte cadmium concentration in never smokers ( 27005419) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Hip circumference adjusted for BMI ( 28552196) Initial alcohol sensitivity ( 30276832) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Menarche (age at onset) ( 27182965 25231870) Midgestational circulating levels of PBDEs ( 28235828) Obesity-related traits ( 23251661) Plasma free amino acid levels ( 30659259) Response to fenofibrate (total cholesterol levels) ( 27002377) Severe COVID-19 infection with respiratory failure (analysis I) ( 32558485) Trunk fat mass ( 28552196) Upper eyelid sagging severity ( 24869959)
Interacting Genes		43 interacting genes: BCL2L11 BMF C12orf40 C14orf119 C17orf67 CHMP5 DLGAP1 DNAL4 DPPA3 DYNC1I1 EWSR1 F13A1 FAM117B GABARAPL2 GPHN GPRIN2 HDAC6 HMBOX1 HOMER3 HSF5 IHO1 KANK2 KIF2B MEOX2 MORN3 MSI2 MYO5A OTUD6A PAK1 PKIA PKIG PRKD3 RASGRP3 SECISBP2L SKAP1 SMCP SPAG8 STXBP4 THAP10 TLK1 TPPP XIAP ZAR1	24 interacting genes: APC DLG1 DLG2 DLG3 DLG4 DLGAP2 DLGAP3 DYNLL1 DYNLL2 FHL2 GRB2 GRIN2A GRIN2C ITSN1 ITSN2 KCNA4 MAGEA11 MAGI2 MYO5A SHANK1 SHANK2 SHANK3 SORBS2 TANC1
Entrez ID		140735	9229
HPRD ID		06489	09260
Ensembl ID		ENSG00000264364	ENSG00000170579
Uniprot IDs		Q96FJ2	A0A0A0MTP4 A8MXQ8 B7Z2J5 O14490 Q6IS01
PDB IDs		2XQQ 3P8M 4D07	5YPO
Enriched GO Terms of Interacting Partners?
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