DYNLL2 and DPPA3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		DYNLL2	DPPA3
Description		dynein light chain LC8-type 2	developmental pluripotency associated 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Centrosome Cytosol Cytoplasmic Dynein Complex Microtubule Plasma Membrane Cilium Postsynaptic Density Membrane Dynein Complex Myosin V Complex Ciliary Tip 9+0 Non-motile Cilium Postsynapse Glutamatergic Synapse	Female Pronucleus Male Pronucleus Nucleus Cytoplasm
	Molecular Function	Protein Binding Identical Protein Binding Protein-containing Complex Binding Dynein Intermediate Chain Binding Dynein Light Intermediate Chain Binding Scaffold Protein Binding	Protein Binding Methylated Histone Binding
	Biological Process	Microtubule-based Process Cilium Assembly	Chromatin Organization Protection Of DNA Demethylation Of Female Pronucleus Negative Regulation Of DNA Demethylation Regulation Of Genetic Imprinting
Pathways		Activation of BMF and translocation to mitochondria Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Macroautophagy MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand Intraflagellar transport RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase HCMV Early Events Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Blood protein levels ( 30072576)	Borderline personality disorder ( 28632202) White matter hyperintensities in ischemic stroke ( 26674333)
Interacting Genes		43 interacting genes: BCL2L11 BMF C12orf40 C14orf119 C17orf67 CHMP5 DLGAP1 DNAL4 DPPA3 DYNC1I1 EWSR1 F13A1 FAM117B GABARAPL2 GPHN GPRIN2 HDAC6 HMBOX1 HOMER3 HSF5 IHO1 KANK2 KIF2B MEOX2 MORN3 MSI2 MYO5A OTUD6A PAK1 PKIA PKIG PRKD3 RASGRP3 SECISBP2L SKAP1 SMCP SPAG8 STXBP4 THAP10 TLK1 TPPP XIAP ZAR1	14 interacting genes: DEPDC5 DYNLL1 DYNLL2 HAUS7 IPO5 KRT27 KRT76 NUP62 PLEKHG4 SERTAD3 SYCE1L TFIP11 TRIB3 ZNF618
Entrez ID		140735	359787
HPRD ID		06489	16331
Ensembl ID		ENSG00000264364	ENSG00000187569
Uniprot IDs		Q96FJ2	Q6W0C5
PDB IDs		2XQQ 3P8M 4D07
Enriched GO Terms of Interacting Partners?
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