CRIP2 and KLF10

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		CRIP2	KLF10
Description		cysteine rich protein 2	Kruppel like factor 10
Image
GO Annotations	Cellular Component	Cell Cortex	Chromatin Nucleus
	Molecular Function	Protein Binding Zinc Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Core Promoter Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Positive Regulation Of Cell Population Proliferation Hemopoiesis	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Cell-cell Signaling Circadian Rhythm Negative Regulation Of Cell Population Proliferation Cellular Response To Starvation Bone Mineralization Somatic Stem Cell Population Maintenance Regulation Of Circadian Rhythm Positive Regulation Of Osteoclast Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Peptide
Pathways
Drugs
Diseases
GWAS			Alanine aminotransferase levels ( 33547301 33339817) Chronic lymphocytic leukemia ( 23770605) IgA nephropathy ( 26028593) Liver enzyme levels (alanine transaminase) ( 33972514) Neurofibrillary tangles ( 31497858) Urate levels ( 31578528)
Interacting Genes		19 interacting genes: APP ATN1 ATP1B1 ATXN1 CDC42 ERBB2 GADD45G GATA4 GATA6 KLF10 NOTCH3 OSGEP PCYT2 PRKG1 PTPN13 SMN1 SPRY2 SRF TK1	17 interacting genes: BOP1 CDK2 CDK6 CRIP2 FBXW7 KAT2B LENG1 PIGC RPL14 SF3B3 SIAH1 SIN3A SNHG29 SP1 TNS1 TULP3 ZNF512B
Entrez ID		1397	7071
HPRD ID		03113	03527
Ensembl ID		ENSG00000182809	ENSG00000155090
Uniprot IDs		P52943	Q13118
PDB IDs		2CU8	2EPA
Enriched GO Terms of Interacting Partners?
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