KLF10 and BOP1

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		KLF10	BOP1
Description		Kruppel like factor 10	BOP1 ribosomal biogenesis factor
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Nucleoplasm Chromosome Nucleolus Preribosome, Large Subunit Precursor PeBoW Complex Ribonucleoprotein Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Core Promoter Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	RNA Binding Protein Binding Ribonucleoprotein Complex Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Cell-cell Signaling Circadian Rhythm Negative Regulation Of Cell Population Proliferation Cellular Response To Starvation Bone Mineralization Somatic Stem Cell Population Maintenance Regulation Of Circadian Rhythm Positive Regulation Of Osteoclast Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Peptide	Ribosomal Large Subunit Assembly Cleavage In ITS2 Between 5.8S RRNA And LSU-rRNA Of Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Maturation Of LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Cell Population Proliferation Ribosome Biogenesis Regulation Of Cell Cycle Regulation Of Signal Transduction By P53 Class Mediator
Pathways			Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301 33339817) Chronic lymphocytic leukemia ( 23770605) IgA nephropathy ( 26028593) Liver enzyme levels (alanine transaminase) ( 33972514) Neurofibrillary tangles ( 31497858) Urate levels ( 31578528)	Dupuytren's disease ( 28886342) FEV1 ( 30804560) Lung function (FVC) ( 30804560) Type 2 diabetes ( 30297969)
Interacting Genes		17 interacting genes: BOP1 CDK2 CDK6 CRIP2 FBXW7 KAT2B LENG1 PIGC RPL14 SF3B3 SIAH1 SIN3A SNHG29 SP1 TNS1 TULP3 ZNF512B	2 interacting genes: KLF10 PES1
Entrez ID		7071	23246
HPRD ID		03527	16558
Ensembl ID		ENSG00000155090	ENSG00000261236
Uniprot IDs		Q13118	Q14137
PDB IDs		2EPA
Enriched GO Terms of Interacting Partners?
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