CRHBP and UCN

Number of citations of the paper that reports this interaction (PubMedID 8612563)
35

Data Source:
BioGRID (pull down)
HPRD (in vivo, in vitro)

		CRHBP	UCN
Description		corticotropin releasing hormone binding protein	urocortin
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Secondary Lysosome Multivesicular Body Endoplasmic Reticulum Golgi Apparatus Microtubule Secretory Granule Dendrite Dense Core Granule Varicosity Perikaryon Axon Terminus	Extracellular Region Dendrite Varicosity Perikaryon Axon Terminus
	Molecular Function	Protein Binding Peptide Binding Corticotropin-releasing Hormone Binding	Neuropeptide Hormone Activity Protein Binding Histone Deacetylase Inhibitor Activity Corticotropin-releasing Hormone Receptor 1 Binding Corticotropin-releasing Hormone Receptor 2 Binding
	Biological Process	Synaptic Transmission, Dopaminergic Inflammatory Response Signal Transduction Female Pregnancy Learning Or Memory Hormone-mediated Signaling Pathway Cellular Response To Potassium Ion Regulated Exocytosis Behavioral Response To Ethanol Regulation Of Corticotropin Secretion Negative Regulation Of Corticotropin Secretion Cellular Response To Calcium Ion Cellular Response To Cocaine Cellular Response To CAMP Cellular Response To Tumor Necrosis Factor Cellular Response To Estrogen Stimulus Cellular Response To Estradiol Stimulus Cellular Response To Xenobiotic Stimulus Regulation Of Cellular Response To Stress Cellular Response To Gonadotropin-releasing Hormone Negative Regulation Of Corticotropin-releasing Hormone Receptor Activity Regulation Of NMDA Receptor Activity	Startle Response Inflammatory Response Response To Oxidative Stress G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Female Pregnancy Sensory Perception Of Sound Associative Learning Aerobic Respiration Negative Regulation Of Gene Expression Response To Auditory Stimulus Pancreatic Juice Secretion Positive Regulation Of Cell Growth Negative Regulation Of Histone Deacetylation Neuron Projection Development Negative Regulation Of Appetite Response To Estradiol Positive Regulation Of Interleukin-6 Production Positive Regulation Of Collagen Biosynthetic Process Positive Regulation Of Peptidyl-serine Phosphorylation Activation Of Protein Kinase A Activity Social Behavior Gastric Emptying Vasodilation Drinking Behavior Negative Regulation Of Apoptotic Process Positive Regulation Of Vascular Permeability Positive Regulation Of CAMP-mediated Signaling Positive Regulation Of Translation Positive Regulation Of DNA Replication Negative Regulation Of Blood Pressure Negative Regulation Of Cell Size Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Hormone Secretion Response To Pain Response To Glucocorticoid Positive Regulation Of Corticotropin Secretion Regulation Of Synaptic Transmission, Glutamatergic Positive Regulation Of Cardiac Muscle Contraction Negative Regulation Of Gastric Acid Secretion Negative Regulation Of Necrotic Cell Death Positive Regulation Of Calcium Ion Import Negative Regulation Of Neuron Death Negative Regulation Of Feeding Behavior Positive Regulation Of Behavioral Fear Response
Pathways		Class B/2 (Secretin family receptors)	Class B/2 (Secretin family receptors) Synthesis, secretion, and deacylation of Ghrelin
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Chronotype ( 30696823) Dental caries (decayed, missing and filled tooth surfaces) ( 31533690)	Crohn's disease ( 23128233)
Interacting Genes		4 interacting genes: DHFR DYNLT1 ERRFI1 UCN	5 interacting genes: CRHBP CRHR1 CRHR2 LEP RAB18
Entrez ID		1393	7349
HPRD ID		08348	02970
Ensembl ID		ENSG00000145708	ENSG00000163794
Uniprot IDs		P24387	P55089
PDB IDs			2RMF 3N96 6PB0 6PB1
Enriched GO Terms of Interacting Partners?
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