TRIM50 and EPM2AIP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TRIM50	EPM2AIP1
Description		tripartite motif containing 50	EPM2A interacting protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Nucleus Cytoplasmic Side Of Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding Zinc Ion Binding Identical Protein Binding Ubiquitin Protein Ligase Activity	Protein Binding Identical Protein Binding
	Biological Process	Protein Ubiquitination	Response To Insulin Positive Regulation Of Glycogen Biosynthetic Process Positive Regulation Of Glycogen (starch) Synthase Activity
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Immune reponse to smallpox (secreted IL-12p40) ( 22610502)	Autism spectrum disorder or schizophrenia ( 28540026) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Subjective response to lithium treatment ( 26503763) Triglyceride levels ( 32203549)
Interacting Genes		40 interacting genes: ARHGAP45 CDK18 CLK2 EFHC2 EPM2AIP1 FAM221B GCC1 HDAC6 IQUB KLHL2 L3MBTL2 LNX1 MEOX2 PIAS2 PLA2G6 RAD23A RSPH14 SNAI1 SPG21 SRC TEPSIN TRAF2 TRIM27 TSGA10IP TSSK3 UBASH3A UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2K UBE2N UBTD1 USP2 XAF1 ZNF438 ZNF620	46 interacting genes: ACTN1 APPL2 ARHGEF5 C1orf50 CBFA2T3 CCNB1IP1 CNTROB CPSF7 DTX3 EMP2 EPM2A FHL3 GFAP HSF2BP KCTD1 KCTD9 KRT16 KRT75 LDB2 LIN52 LNX1 MAD2L1 MEOX2 MX1 NOC4L OTUD7B PICK1 PRTFDC1 PSMA7 RBMY1F RBMY1J REL SERPINF1 SWSAP1 TFIP11 TNFAIP1 TNKS TRA2B TRIM50 TRIM54 USP54 VPS52 ZBTB14 ZIM2 ZNF620 ZSCAN18
Entrez ID		135892	9852
HPRD ID		15566	07445
Ensembl ID		ENSG00000146755	ENSG00000178567
Uniprot IDs		B7ZLG2 Q2M204 Q86XT4	Q7L775
PDB IDs
Enriched GO Terms of Interacting Partners?
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