NCOA7 and TNFRSF25

		NCOA7	TNFRSF25
Description		nuclear receptor coactivator 7	TNF receptor superfamily member 25
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Extracellular Region Cytosol Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Protein Binding Nuclear Receptor Binding Nuclear Receptor Coactivator Activity	Tumor Necrosis Factor-activated Receptor Activity Signaling Receptor Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Response To Oxidative Stress Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Cellular Response To Oxidative Stress Negative Regulation Of Peptidyl-cysteine S-nitrosylation Negative Regulation Of Oxidative Stress-induced Neuron Death	Apoptotic Process Signal Transduction Cell Surface Receptor Signaling Pathway Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of Apoptotic Process Apoptotic Signaling Pathway
Pathways			TNFs bind their physiological receptors
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Brugada syndrome ( 23872634) Endometrial cancer ( 30093612 27135401) Endometrial cancer (endometrioid histology) ( 30093612) Endometrial endometrioid carcinoma ( 27135401) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494) Hip index ( 34021172) Immature fraction of reticulocytes ( 32888494) Leftâ€“right brain asymmetry ( 33723403) Menarche (age at onset) ( 25231870) Migraine ( 27322543) Night sleep phenotypes ( 27126917) Red blood cell count ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Serum metabolite concentrations in chronic kidney disease ( 33838163) Subcortical volume (MOSTest) ( 32665545) Systolic blood pressure ( 30224653 30578418) Urate levels ( 31578528) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		5 interacting genes: AHR ARNT ESR1 ESR2 TNFRSF25	12 interacting genes: BAG4 DAP3 EIF2S2 MAPK1 NCOA7 NPPB SLC2A5 TNFRSF1A TNFSF12 TNFSF15 TRADD TRAF2
Entrez ID		135112	8718
HPRD ID		14814	04532
Ensembl ID		ENSG00000111912	ENSG00000215788
Uniprot IDs		B3KXK4 H0Y5F6 Q8N3C8 Q8NI08	Q93038
PDB IDs			5YGP 5YGS
Enriched GO Terms of Interacting Partners?
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