ZFP42 and LHX2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ZFP42	LHX2
Description		ZFP42 zinc finger protein	LIM homeobox 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Transcription Regulator Complex Cytoplasm PcG Protein Complex	Chromatin Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Male Gonad Development Female Gonad Development Meiotic Cell Cycle	Neural Tube Closure Hair Follicle Development Regulation Of Transcription By RNA Polymerase II Axon Guidance Mesoderm Development Dorsal/ventral Pattern Formation Olfactory Bulb Development Telencephalon Regionalization Cerebral Cortex Development Neuron Differentiation Maintenance Of Epithelial Cell Apical/basal Polarity Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Axon Extension Negative Regulation Of Neurogenesis Retina Development In Camera-type Eye Positive Regulation Of Neural Precursor Cell Proliferation Negative Regulation Of Transcription Regulatory Region DNA Binding
Pathways			Regulation of expression of SLITs and ROBOs
Drugs
Diseases
GWAS		Cortisol levels (saliva) ( 28843169) LDL levels x SSRI levels (escitalopram or citalopram) interaction in schizophrenia or bipolar disorder ( 33824429) Testicular germ cell tumor ( 28604728 28604732) Visceral fat ( 30942860)	Asthma exacerbations in inhaled corticosteroid treatment ( 30697902) Blond vs. brown/black hair color ( 30531825) Depression ( 29700475) Hair color ( 29662168) Mercury levels ( 26025379) Post-traumatic stress disorder ( 25456346) Thrombin-activatable fibrinolysis inhibitor activation peptide ( 29378355) Waist circumference ( 23966867)
Interacting Genes		8 interacting genes: EED LHX2 MEOX2 PIAS2 RNF4 RYBP SUMO1 YAF2	29 interacting genes: ANKS1A ARHGAP32 BEND2 CITED2 DNMT3L ENG FLYWCH1 HOMER3 HOXC8 KHK LDB1 LGALSL LNX1 LONRF1 MORF4L1 MORN3 MSX1 OSMR PAX6 POU4F2 PPIL1 RLIM TCEANC TCP11L1 TLK1 TRAPPC2L UBTFL1 ZFP42 ZNF511
Entrez ID		132625	9355
HPRD ID		15726	04786
Ensembl ID		ENSG00000179059	ENSG00000106689
Uniprot IDs		Q96MM3	B3KNJ5 P50458
PDB IDs
Enriched GO Terms of Interacting Partners?
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