ADK and FICD

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		ADK	FICD
Description		adenosine kinase	FIC domain protein adenylyltransferase
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Plasma Membrane	Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	RNA Binding Adenosine Kinase Activity ATP Binding Metal Ion Binding	Protein Binding ATP Binding Hsp70 Protein Binding Identical Protein Binding Protein Homodimerization Activity Protein Adenylylhydrolase Activity Chaperone Binding Protein Adenylyltransferase Activity
	Biological Process	Purine Ribonucleoside Salvage DATP Biosynthetic Process Ribonucleoside Monophosphate Biosynthetic Process Phosphorylation AMP Salvage	Response To Unfolded Protein Protein Adenylylation Negative Regulation Of GTPase Activity Response To Endoplasmic Reticulum Stress Protein Deadenylylation Regulation Of IRE1-mediated Unfolded Protein Response
Pathways		Purine salvage
Drugs		Adenosine phosphate 7-(5-DEOXY-BETA-D-RIBOFURANOSYL)-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE 5-[4-(DIMETHYLAMINO)PHENYL]-6-[(6-MORPHOLIN-4-YLPYRIDIN-3-YL)ETHYNYL]PYRIMIDIN-4-AMINE
Diseases
GWAS		Adult body size ( 32376654) Cardiac troponin-I levels ( 31014085) Diverticular disease ( 30177863) Drug experimentation measurement ( 30718321) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Hypospadias ( 25108383) Lymphocyte counts ( 32888494) Permanent tooth development ( 21931568) Platelet count ( 32888494) Plateletcrit ( 32888494) Primary tooth development (number of teeth) ( 23704328) Primary tooth development (time to first tooth eruption) ( 23704328) Refractive error ( 32231278) Soluble interleukin-2 receptor subunit alpha ( 26293465) Systolic blood pressure ( 30578418)	Acne (severe) ( 24927181) Obesity-related traits ( 23251661) Response to methotrexate in juvenile idiopathic arthritis ( 24709693)
Interacting Genes		3 interacting genes: FICD PLEKHA5 SRD5A3	2 interacting genes: ADK HTT
Entrez ID		132	11153
HPRD ID		00039	13723
Ensembl ID		ENSG00000156110	ENSG00000198855
Uniprot IDs		A0A140VJE0 A0A5F9ZH72 A0A5F9ZHJ1 P55263	A0A024RBM8 Q9BVA6
PDB IDs		1BX4 2I6A 2I6B 4O1L	4U04 4U07 4U0S 4U0U 4U0Z 6I7G 6I7H 6I7I 6I7J 6I7K 6I7L
Enriched GO Terms of Interacting Partners?
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