FICD and ADK

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		FICD	ADK
Description		FIC domain protein adenylyltransferase	adenosine kinase
Image
GO Annotations	Cellular Component	Integral Component Of Endoplasmic Reticulum Membrane	Nucleus Nucleoplasm Cytosol Plasma Membrane
	Molecular Function	Protein Binding ATP Binding Hsp70 Protein Binding Identical Protein Binding Protein Homodimerization Activity Protein Adenylylhydrolase Activity Chaperone Binding Protein Adenylyltransferase Activity	RNA Binding Adenosine Kinase Activity ATP Binding Metal Ion Binding
	Biological Process	Response To Unfolded Protein Protein Adenylylation Negative Regulation Of GTPase Activity Response To Endoplasmic Reticulum Stress Protein Deadenylylation Regulation Of IRE1-mediated Unfolded Protein Response	Purine Ribonucleoside Salvage DATP Biosynthetic Process Ribonucleoside Monophosphate Biosynthetic Process Phosphorylation AMP Salvage
Pathways			Purine salvage
Drugs			Adenosine phosphate 7-(5-DEOXY-BETA-D-RIBOFURANOSYL)-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE 5-[4-(DIMETHYLAMINO)PHENYL]-6-[(6-MORPHOLIN-4-YLPYRIDIN-3-YL)ETHYNYL]PYRIMIDIN-4-AMINE
Diseases
GWAS		Acne (severe) ( 24927181) Obesity-related traits ( 23251661) Response to methotrexate in juvenile idiopathic arthritis ( 24709693)	Adult body size ( 32376654) Cardiac troponin-I levels ( 31014085) Diverticular disease ( 30177863) Drug experimentation measurement ( 30718321) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Hypospadias ( 25108383) Lymphocyte counts ( 32888494) Permanent tooth development ( 21931568) Platelet count ( 32888494) Plateletcrit ( 32888494) Primary tooth development (number of teeth) ( 23704328) Primary tooth development (time to first tooth eruption) ( 23704328) Refractive error ( 32231278) Soluble interleukin-2 receptor subunit alpha ( 26293465) Systolic blood pressure ( 30578418)
Interacting Genes		2 interacting genes: ADK HTT	3 interacting genes: FICD PLEKHA5 SRD5A3
Entrez ID		11153	132
HPRD ID		13723	00039
Ensembl ID		ENSG00000198855	ENSG00000156110
Uniprot IDs		A0A024RBM8 Q9BVA6	A0A140VJE0 A0A5F9ZH72 A0A5F9ZHJ1 P55263
PDB IDs		4U04 4U07 4U0S 4U0U 4U0Z 6I7G 6I7H 6I7I 6I7J 6I7K 6I7L	1BX4 2I6A 2I6B 4O1L
Enriched GO Terms of Interacting Partners?
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