PPP1R21 and SH2D2A

Number of citations of the paper that reports this interaction (PubMedID 25814554)
26

Data Source:
BioGRID (two hybrid)

		PPP1R21	SH2D2A
Description		protein phosphatase 1 regulatory subunit 21	SH2 domain containing 2A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Early Endosome Membrane	Cytoplasm Cytosol
	Molecular Function		Protein Binding SH3 Domain Binding
	Biological Process		Angiogenesis Signal Transduction Cell Population Proliferation Cell Differentiation
Pathways			VEGFA-VEGFR2 Pathway
Drugs
Diseases
GWAS		Chronotype ( 30696823) Colorectal cancer ( 30529582) Educational attainment ( 27046643) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Joint mobility (Beighton score) ( 27182965) Liver enzyme levels (alkaline phosphatase) ( 33972514) Mean corpuscular hemoglobin concentration ( 29403010) Prudent dietary pattern ( 28644415) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494 27863252) Serum alkaline phosphatase levels ( 33547301)	Autoimmune thyroid disease ( 32581359) Platelet count ( 32888494 27863252) Plateletcrit ( 32888494) SjÃ¶gren's syndrome ( 28076899)
Interacting Genes		6 interacting genes: FBXO7 MTNR1B RTN4 SH2D2A SH3GL2 ZDHHC17	35 interacting genes: APPL1 AR ARID5A CRK DAPK1 EGFR ERBB2 ERBB3 ERBB4 GAB1 ITK KDR KIT LCK LINC02875 LNX1 LRRFIP1 LRRK1 MAP3K2 MAPK7 MET MFHAS1 NAA16 PLCG1 PPP1R21 SOCS3 SPTB STAT3 SYK TSC1 TXK VCP ZHX3 ZSCAN1 ZYG11B
Entrez ID		129285	9047
HPRD ID		17294	05152
Ensembl ID		ENSG00000162869	ENSG00000027869
Uniprot IDs		Q6ZMI0	Q5UBZ2 Q5UBZ3 Q9NP31
PDB IDs
Enriched GO Terms of Interacting Partners?
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