ZNF280A and PDE4C

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ZNF280A	PDE4C
Description		zinc finger protein 280A	phosphodiesterase 4C
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Extracellular Space Nucleus Cytosol Cilium Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding	3',5'-cyclic-nucleotide Phosphodiesterase Activity 3',5'-cyclic-AMP Phosphodiesterase Activity Metal Ion Binding
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II	CAMP Catabolic Process Signal Transduction
Pathways			DARPP-32 events G alpha (s) signalling events
Drugs			Caffeine Dyphylline Iloprost Amrinone Roflumilast Piclamilast Crisaborole Ibudilast Exisulind Trapidil
Diseases
GWAS		Metabolite levels ( 23823483)	Abdominal subcutaneous adipose tissue volume ( 34128465) Apolipoprotein B levels ( 32203549) Body shape index ( 34021172) LDL cholesterol levels ( 32203549) Low density lipoprotein cholesterol levels ( 32154731) Urate levels ( 31578528) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		8 interacting genes: CABP5 CALM1 CALM2 CALM3 EIF1AD ENOPH1 KDM1A PDE4C	10 interacting genes: DDIT4L GDF15 GSC2 KLRK1 MEOX1 MEOX2 OSGIN1 PAX6 SRI ZNF280A
Entrez ID		129025	5143
HPRD ID		18129	02529
Ensembl ID		ENSG00000169548	ENSG00000105650
Uniprot IDs		A0A0G2JN84 P59817	O43849 P78505 Q08493 Q32MM7 Q7KYS4
PDB IDs			1LXU 2QYM
Enriched GO Terms of Interacting Partners?
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